| Title |
Decrease in TSH levels after lactose restriction in Hashimoto’s thyroiditis patients with lactose intolerance
|
|---|---|
| Published in |
Endocrine, September 2013
|
| DOI | 10.1007/s12020-013-0065-1 |
| Pubmed ID | |
| Authors |
Mehmet Asik, Fahri Gunes, Emine Binnetoglu, Mustafa Eroglu, Neslihan Bozkurt, Hacer Sen, Erdem Akbal, Coskun Bakar, Yavuz Beyazit, Kubilay Ukinc |
| Abstract |
We aimed to evaluate the prevalence of lactose intolerance (LI) in patients with Hashimoto's thyroiditis (HT) and the effects of lactose restriction on thyroid function in these patients. Eighty-three HT patients taking L-thyroxine (LT4) were enrolled, and lactose tolerance tests were performed on all patients. Lactose intolerance was diagnosed in 75.9 % of the patients with HT. Thirty-eight patients with LI were started on a lactose-restricted diet for 8 weeks. Thirty-eight patients with LI (30 euthyroid and 8 with subclinical hypothyroidism), and 12 patients without LI were included in the final analysis. The level of TSH significantly decreased in the euthyroid and subclinical hypothyroid patients with LI [from 2.06 ± 1.02 to 1.51 ± 1.1 IU/mL and from 5.45 ± 0.74 to 2.25 ± 1.88 IU/mL, respectively (both P < 0.05)]. However, the level of TSH in patients without LI did not change significantly over the 8 weeks (P > 0.05). Lactose intolerance occurs at a high frequency in HT patients. Lactose restriction leads to decreased levels of TSH, and LI should be considered in hypothyroid patients who require increasing LT4 doses, have irregular TSH levels and are resistant to LT4 treatment. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 50% |
| Brazil | 1 | 25% |
| United Kingdom | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 1% |
| Unknown | 87 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 23 | 26% |
| Student > Master | 9 | 10% |
| Other | 7 | 8% |
| Student > Postgraduate | 4 | 5% |
| Professor | 3 | 3% |
| Other | 10 | 11% |
| Unknown | 32 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 27% |
| Nursing and Health Professions | 13 | 15% |
| Agricultural and Biological Sciences | 6 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Immunology and Microbiology | 2 | 2% |
| Other | 3 | 3% |
| Unknown | 37 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 45. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2021.
All research outputs
#906,518
of 25,152,132 outputs
Outputs from Endocrine
#38
of 1,897 outputs
Outputs of similar age
#7,871
of 212,052 outputs
Outputs of similar age from Endocrine
#2
of 13 outputs
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So far Altmetric has tracked 1,897 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 98% of its peers.
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