| Title |
Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin
|
|---|---|
| Published in |
Thyroid Research, August 2011
|
| DOI | 10.1186/1756-6614-4-s1-s1 |
| Pubmed ID | |
| Authors |
Juliane Braun, Stefan Hüttelmaier |
| Abstract |
Thyroid cancer is one of the most common malignancies of the endocrine system with increasing incidence. The vast majority of thyroid carcinomas derive from thyroid hormone producing follicular cells. Carcinomas of follicular origin are classified as follicular (FTCs), papillary (PTCs), partially differentiated (PDTCs) or anaplastic (ATCs) thyroid carcinomas. While FTCs and PTCs can be managed effectively, ATCs are considered one of the most lethal human cancers. Despite the identification of various genetic alterations, pathogenic mechanisms promoting the progression of thyroid carcinomas are still largely elusive. Over the recent years, aberrant microRNA expression was revealed in all as yet analyzed human cancers, including thyroid carcinomas. In view of the rapidly evolving perception that deregulated microRNA expression serves a pivotal role in tumor progression, microRNAs provide powerful tools for the diagnosis of thyroid carcinomas as well as the identification of potential therapeutic targets. Here, we summarize recent findings on microRNA signatures in thyroid carcinomas of follicular origin and discuss how deregulated microRNA expression could promote cancer progression. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 4% |
| United States | 1 | 4% |
| France | 1 | 4% |
| Unknown | 25 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 36% |
| Student > Bachelor | 3 | 11% |
| Other | 3 | 11% |
| Student > Doctoral Student | 2 | 7% |
| Professor | 2 | 7% |
| Other | 6 | 21% |
| Unknown | 2 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 11 | 39% |
| Biochemistry, Genetics and Molecular Biology | 9 | 32% |
| Medicine and Dentistry | 5 | 18% |
| Unknown | 3 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2011.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Thyroid Research
#160
of 216 outputs
Outputs of similar age
#108,449
of 130,473 outputs
Outputs of similar age from Thyroid Research
#5
of 5 outputs
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