Title |
A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans
|
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Published in |
Psychopharmacology, March 2013
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DOI | 10.1007/s00213-013-3039-3 |
Pubmed ID | |
Authors |
Michael E. Saladin, Kevin M. Gray, Aimee L. McRae-Clark, Steven D. LaRowe, Sharon D. Yeatts, Nathaniel L. Baker, Karen J. Hartwell, Kathleen T. Brady |
Abstract |
This study examined the effects of propranolol vs. placebo, administered immediately after a "retrieval" session of cocaine cue exposure (CCE), on craving and physiological responses occurring 24 h later during a subsequent "test" session of CCE. It was hypothesized that compared to placebo-treated cocaine-dependent (CD) individuals, propranolol-treated CD individuals would evidence attenuated craving and physiological reactivity during the test session. Secondarily, it was expected that group differences identified in the test session would be evident at a 1-week follow-up CCE session. Exploratory analyses of treatment effects on cocaine use were also performed at follow-up. |
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Country | Count | As % |
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Canada | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
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Portugal | 1 | <1% |
Germany | 1 | <1% |
France | 1 | <1% |
Unknown | 110 | 97% |
Demographic breakdown
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Student > Ph. D. Student | 23 | 20% |
Student > Bachelor | 21 | 19% |
Researcher | 19 | 17% |
Student > Master | 12 | 11% |
Other | 8 | 7% |
Other | 16 | 14% |
Unknown | 14 | 12% |
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Medicine and Dentistry | 9 | 8% |
Agricultural and Biological Sciences | 8 | 7% |
Nursing and Health Professions | 3 | 3% |
Other | 8 | 7% |
Unknown | 17 | 15% |