| Title |
Timing of Prenatal Stressors and Autism
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, August 2005
|
| DOI | 10.1007/s10803-005-5037-8 |
| Pubmed ID | |
| Authors |
D. Q. Beversdorf, S. E. Manning, A. Hillier, S. L. Anderson, R. E. Nordgren, S. E. Walters, H. N. Nagaraja, W. C. Cooley, S. E. Gaelic, M. L. Bauman |
| Abstract |
Recent evidence supports a role for genetics in autism, but other findings are difficult to reconcile with a purely genetic cause. Pathological changes in the cerebellum in autism are thought to correspond to an event before 30-32 weeks gestation. Our purpose was to determine whether there is an increased incidence of stressors in autism before this time period. Surveys regarding incidence and timing of prenatal stressors were distributed to specialized schools and clinics for autism and Down syndrome, and to mothers of children without neurodevelopmental diagnoses in walk-in clinics. Incidence of stressors during each 4-week block of pregnancy was recorded. Incidence of stressors in the blocks prior to and including the predicted time period (21-32 weeks gestation) in each group of surveys was compared to the other prenatal blocks. A higher incidence of prenatal stressors was found in autism at 21-32 weeks gestation, with a peak at 25-28 weeks. This does support the possibility of prenatal stressors as a potential contributor to autism, with the timing of stressors consistent with the embryological age suggested by neuroanatomical findings seen in the cerebellum in autism. Future prospective studies would be needed to confirm this finding. |
Mendeley readers
The data shown below were compiled from readership statistics for 301 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Canada | 2 | <1% |
| Japan | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 295 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 47 | 16% |
| Student > Master | 42 | 14% |
| Researcher | 40 | 13% |
| Student > Bachelor | 39 | 13% |
| Student > Doctoral Student | 25 | 8% |
| Other | 60 | 20% |
| Unknown | 48 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 62 | 21% |
| Medicine and Dentistry | 45 | 15% |
| Agricultural and Biological Sciences | 39 | 13% |
| Neuroscience | 37 | 12% |
| Biochemistry, Genetics and Molecular Biology | 12 | 4% |
| Other | 42 | 14% |
| Unknown | 64 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2016.
All research outputs
#2,100,546
of 23,867,274 outputs
Outputs from Journal of Autism and Developmental Disorders
#930
of 5,240 outputs
Outputs of similar age
#3,243
of 58,463 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#2
of 11 outputs
Altmetric has tracked 23,867,274 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,240 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,463 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.