| Title |
Glass ionomer cement inhibits secondary caries in an in vitro biofilm model
|
|---|---|
| Published in |
Clinical Oral Investigations, July 2017
|
| DOI | 10.1007/s00784-017-2184-1 |
| Pubmed ID | |
| Authors |
Norbert Krämer, Miriam Schmidt, Susanne Lücker, Eugen Domann, Roland Frankenberger |
| Abstract |
The objective of this study was to investigate the effect of different glass ionomer cements on secondary caries inhibition in a fully automated in vitro biofilm model. One hundred and twenty-four extracted third molars received class V cavities and were filled with one conventional (Ketac Molar/KM), and two resin-modified glass ionomer cements (Photac Fil/PF, Ketac N100/KN, 3M Espe). A bonded resin composite (Single Bond Plus/Filtek Supreme XTE) served as control. After 14 days water storage at 37 °C, specimens were thermocycled (10,000 × 5/55 °C). Over a period of 10 days, specimens were subjected to cariogenic challenge for 3/4/6 h/day. Demineralization was caused by Streptococcus mutans (DSM 20523) alternatingly being rinsed over specimens using artificial saliva. After biological loading, teeth were cut longitudinally and demineralization depths were evaluated at the margins and at a distance of 0.5 mm from the margins using fluorescence microscopy. Marginal quality was investigated under a SEM at ×200 magnification. Four-hour demineralization depths were for enamel margins (EM), enamel (E), dentin margin (DM), and dentin (D) (μm ± SD): KM: EM 12 ± 8, E 33 ± 7, DM 56 ± 11, D 79 ± 6; PF: EM 19 ± 13, E 34 ± 13, DM 53 ± 10, D 77 ± 12; and KN: EM 26 ± 5, E 38 ± 6, DM 57 ± 11, D 71 ± 7. For all glass ionomer cements (GICs), demineralization depth at the margins was less compared to 0.5 mm distance, with demineralization depth having been correlated to duration of cariogenic challenge (ANOVA [mod. LSD, p < 0.05]). Compared to the bonded resin composite, all GICs exhibited caries inhibition at restoration margins in enamel and dentin. Fluoride-releasing GIC materials exhibit a secondary caries inhibiting effect in vitro. Glass ionomer cements have a higher secondary caries inhibiting effect than resin composites. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 107 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 13% |
| Student > Bachelor | 13 | 12% |
| Student > Ph. D. Student | 8 | 7% |
| Student > Postgraduate | 7 | 7% |
| Researcher | 6 | 6% |
| Other | 17 | 16% |
| Unknown | 42 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 45% |
| Biochemistry, Genetics and Molecular Biology | 2 | 2% |
| Materials Science | 2 | 2% |
| Chemistry | 2 | 2% |
| Social Sciences | 1 | <1% |
| Other | 2 | 2% |
| Unknown | 50 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2017.
All research outputs
#20,438,227
of 22,992,311 outputs
Outputs from Clinical Oral Investigations
#1,037
of 1,426 outputs
Outputs of similar age
#276,283
of 316,523 outputs
Outputs of similar age from Clinical Oral Investigations
#9
of 12 outputs
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