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Mendeley readers
Attention Score in Context
Title |
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
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Published in |
Nature Reviews Genetics, August 2006
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DOI | 10.1038/nrg1879 |
Pubmed ID | |
Authors |
Jeffrey A. Engelman, Ji Luo, Lewis C. Cantley |
Abstract |
Phosphatidylinositol 3-kinases (PI3Ks) evolved from a single enzyme that regulates vesicle trafficking in unicellular eukaryotes into a family of enzymes that regulate cellular metabolism and growth in multicellular organisms. In this review, we examine how the PI3K pathway has evolved to control these fundamental processes, and how this pathway is in turn regulated by intricate feedback and crosstalk mechanisms. In light of the recent advances in our understanding of the function of PI3Ks in the pathogenesis of diabetes and cancer, we discuss the exciting therapeutic opportunities for targeting this pathway to treat these diseases. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,479 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 18 | 1% |
United Kingdom | 7 | <1% |
Netherlands | 5 | <1% |
Japan | 3 | <1% |
Germany | 3 | <1% |
France | 2 | <1% |
China | 2 | <1% |
Chile | 2 | <1% |
Australia | 1 | <1% |
Other | 7 | <1% |
Unknown | 1429 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 328 | 22% |
Researcher | 211 | 14% |
Student > Master | 181 | 12% |
Student > Bachelor | 151 | 10% |
Student > Doctoral Student | 90 | 6% |
Other | 228 | 15% |
Unknown | 290 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 414 | 28% |
Biochemistry, Genetics and Molecular Biology | 306 | 21% |
Medicine and Dentistry | 198 | 13% |
Chemistry | 51 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 49 | 3% |
Other | 130 | 9% |
Unknown | 331 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2023.
All research outputs
#1,689,878
of 23,509,253 outputs
Outputs from Nature Reviews Genetics
#801
of 2,616 outputs
Outputs of similar age
#2,915
of 66,312 outputs
Outputs of similar age from Nature Reviews Genetics
#2
of 16 outputs
Altmetric has tracked 23,509,253 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,616 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.2. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 66,312 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.