Title |
Drug discovery from natural sources
|
---|---|
Published in |
The AAPS Journal, April 2006
|
DOI | 10.1007/bf02854894 |
Pubmed ID | |
Authors |
Young-Won Chin, Marcy J. Balunas, Hee Byung Chai, A. Douglas Kinghorn |
Abstract |
Organic compounds from terrestrial and marine organisms have extensive past and present use in the treatment of many diseases and serve as compounds of interest both in their natural form and as templates for synthetic modification. Over 20 new drugs launched on the market between 2000 and 2005, originating from terrestrial plants, terrestrial microorganisms, marine organisms, and terrestrial vertebrates and invertebrates, are described. These approved substances, representative of very wide chemical diversity, together with several other natural products or their analogs undergoing clinical trials, continue to demonstrate the importance of compounds from natural sources in modern drug discovery efforts. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 5 | <1% |
United States | 3 | <1% |
Chile | 2 | <1% |
Poland | 2 | <1% |
Brazil | 2 | <1% |
South Africa | 2 | <1% |
Brunei Darussalam | 1 | <1% |
Sweden | 1 | <1% |
Panama | 1 | <1% |
Other | 9 | 2% |
Unknown | 544 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 123 | 22% |
Student > Master | 101 | 18% |
Researcher | 58 | 10% |
Student > Bachelor | 48 | 8% |
Student > Doctoral Student | 25 | 4% |
Other | 78 | 14% |
Unknown | 139 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 131 | 23% |
Chemistry | 118 | 21% |
Biochemistry, Genetics and Molecular Biology | 67 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 38 | 7% |
Medicine and Dentistry | 27 | 5% |
Other | 39 | 7% |
Unknown | 152 | 27% |