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Mendeley readers
| Title |
The anticancer effects of HDAC inhibitors require the immune system
|
|---|---|
| Published in |
OncoImmunology, January 2014
|
| DOI | 10.4161/onci.27414 |
| Pubmed ID | |
| Authors |
Alison C West, Mark J Smyth, Ricky W Johnstone |
| Abstract |
Histone deacetylase inhibitors (HDACis) are known to exert immunomodulatory effects. We have recently demonstrated that the therapeutic efficacy of HDACis against aggressive B-cell lymphoma and colon carcinoma relies on a functional immune system, in particular on the production of interferon γ (IFNγ). Our findings provide a rationale for the combination of HDACis with immunotherapeutic agents in the clinic. |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Israel | 1 | 2% |
| United States | 1 | 2% |
| Austria | 1 | 2% |
| Unknown | 55 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 20% |
| Researcher | 11 | 19% |
| Other | 7 | 12% |
| Student > Doctoral Student | 6 | 10% |
| Student > Bachelor | 5 | 8% |
| Other | 11 | 19% |
| Unknown | 7 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 27% |
| Biochemistry, Genetics and Molecular Biology | 13 | 22% |
| Agricultural and Biological Sciences | 6 | 10% |
| Immunology and Microbiology | 5 | 8% |
| Chemistry | 3 | 5% |
| Other | 7 | 12% |
| Unknown | 9 | 15% |