| Title |
The Current Status of iPS Cells in Cardiac Research and Their Potential for Tissue Engineering and Regenerative Medicine
|
|---|---|
| Published in |
Stem Cell Reviews and Reports, January 2014
|
| DOI | 10.1007/s12015-013-9487-7 |
| Pubmed ID | |
| Authors |
Ana M. Martins, Gordana Vunjak-Novakovic, Rui L. Reis |
| Abstract |
The recent availability of human cardiomyocytes derived from induced pluripotent stem (iPS) cells opens new opportunities to build in vitro models of cardiac disease, screening for new drugs, and patient-specific cardiac therapy. Notably, the use of iPS cells enables studies in the wide pool of genotypes and phenotypes. We describe progress in reprogramming of induced pluripotent stem (iPS) cells towards the cardiac lineage/differentiation. The focus is on challenges of cardiac disease modeling using iPS cells and their potential to produce safe, effective and affordable therapies/applications with the emphasis of cardiac tissue engineering. We also discuss implications of human iPS cells to biological research and some of the future needs. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 1% |
| Colombia | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 132 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 27% |
| Student > Master | 19 | 14% |
| Student > Bachelor | 18 | 13% |
| Researcher | 17 | 13% |
| Student > Doctoral Student | 8 | 6% |
| Other | 17 | 13% |
| Unknown | 20 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 32 | 24% |
| Biochemistry, Genetics and Molecular Biology | 27 | 20% |
| Engineering | 20 | 15% |
| Medicine and Dentistry | 18 | 13% |
| Materials Science | 5 | 4% |
| Other | 11 | 8% |
| Unknown | 23 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2020.
All research outputs
#3,274,712
of 25,374,647 outputs
Outputs from Stem Cell Reviews and Reports
#88
of 1,036 outputs
Outputs of similar age
#38,757
of 336,900 outputs
Outputs of similar age from Stem Cell Reviews and Reports
#2
of 12 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,036 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,900 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.