Title |
Vapor, Dust, and Smoke Exposure in Relation to Adult-Onset Asthma and Chronic Respiratory Symptoms
|
---|---|
Published in |
American Journal of Epidemiology, May 2006
|
DOI | 10.1093/aje/kwj144 |
Pubmed ID | |
Authors |
Tricia D LeVan, Woon-Puay Koh, Hin-Peng Lee, David Koh, Mimi C Yu, Stephanie J London |
Abstract |
Occupational factors contribute to a significant fraction of respiratory disease and symptoms. The authors evaluated the role of occupational exposures in asthma, chronic bronchitis, and respiratory symptoms in the Singapore Chinese Health Study, a population-based cohort of adults aged 45-74 years at enrollment in 1993-1998. Information on occupations and occupational exposures was collected at enrollment for 52,325 subjects for whom respiratory outcomes were obtained via follow-up interviews in 1999-2004. Exposure to dusts from cotton, wood, metal, minerals, and/or asbestos was associated with nonchronic cough and/or phlegm (odds ratio (OR) = 1.19, 95% confidence interval (CI): 1.08, 1.30), chronic bronchitis (OR = 1.26, 95% CI: 1.01, 1.57), and adult-onset asthma (OR = 1.14, 95% CI: 1.00, 1.30). Cotton dust was the major contributor to respiratory symptoms. Vapor exposure from chemical solvents, dyes, cooling oils, paints, wood preservatives, and/or pesticides was associated with nonchronic cough or phlegm (OR = 1.14, 95% CI: 1.03, 1.27), chronic dry cough (OR = 1.55, 95% CI: 1.19, 2.01), and adult-onset asthma (OR = 1.34, 95% CI: 1.15, 1.56). Chemical solvents, cooling oils, and pesticides were the major contributors to respiratory symptoms. These data support the role of occupational exposures in the etiology of respiratory illness in a population-based cohort in Singapore with a low prevalence of atopic illness. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Korea, Republic of | 1 | 1% |
Malawi | 1 | 1% |
United Kingdom | 1 | 1% |
Singapore | 1 | 1% |
Spain | 1 | 1% |
Unknown | 79 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 20% |
Student > Master | 15 | 18% |
Student > Ph. D. Student | 10 | 12% |
Student > Bachelor | 9 | 11% |
Professor | 6 | 7% |
Other | 12 | 14% |
Unknown | 15 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 36 | 43% |
Environmental Science | 6 | 7% |
Agricultural and Biological Sciences | 5 | 6% |
Nursing and Health Professions | 3 | 4% |
Immunology and Microbiology | 3 | 4% |
Other | 14 | 17% |
Unknown | 17 | 20% |