| Title |
On the road to bioartificial organs
|
|---|---|
| Published in |
Pflügers Archiv - European Journal of Physiology, April 2014
|
| DOI | 10.1007/s00424-014-1504-4 |
| Pubmed ID | |
| Authors |
X. Ren, H. C. Ott |
| Abstract |
Biological organs are highly orchestrated systems with well-coordinated positioning, grouping, and interaction of different cell types within their specialized extracellular environment. Bioartificial organs are intended to be functional replacements of native organs generated through bioengineering techniques and hold the potential to alleviate donor organ shortage for transplantation. The development, production, and evaluation of such bioartificial organs require synergistic efforts of biology, material science, engineering, and medicine. In this review, we highlight the emerging platforms enabling structured assembly of multiple cell types into functional grafts and discuss recent advances and challenges in the development of bioartificial organs, including cell sources, in vitro organ culture, in vivo evaluation, and clinical considerations. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Croatia | 1 | 1% |
| Germany | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 66 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 17% |
| Student > Master | 10 | 14% |
| Student > Bachelor | 10 | 14% |
| Student > Ph. D. Student | 8 | 12% |
| Other | 5 | 7% |
| Other | 12 | 17% |
| Unknown | 12 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 14 | 20% |
| Agricultural and Biological Sciences | 11 | 16% |
| Medicine and Dentistry | 9 | 13% |
| Biochemistry, Genetics and Molecular Biology | 8 | 12% |
| Materials Science | 5 | 7% |
| Other | 9 | 13% |
| Unknown | 13 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2015.
All research outputs
#18,550,468
of 23,815,455 outputs
Outputs from Pflügers Archiv - European Journal of Physiology
#1,512
of 1,973 outputs
Outputs of similar age
#158,227
of 227,111 outputs
Outputs of similar age from Pflügers Archiv - European Journal of Physiology
#25
of 31 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,973 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,111 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.