Title |
Serological Assessment for Celiac Disease in IgA Deficient Adults
|
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Published in |
PLOS ONE, April 2014
|
DOI | 10.1371/journal.pone.0093180 |
Pubmed ID | |
Authors |
Ning Wang, Lennart Truedsson, Kerstin Elvin, Bengt A. Andersson, Johan Rönnelid, Lucia Mincheva-Nilsson, Annica Lindkvist, Jonas F. Ludvigsson, Lennart Hammarström, Charlotte Dahle |
Abstract |
Selective immunoglobulin A deficiency is the most common primary immunodeficiency disorder that is strongly overrepresented among patients with celiac disease (CD). IgG antibodies against tissue transglutaminase (tTG) and deamidated gliadin peptides (DGP) serve as serological markers for CD in IgA deficient individuals, although the diagnostic value remains uncertain. The aim of this study was to investigate the prevalence of these markers in a large cohort of IgA deficient adults with confirmed or suspected CD and relate the findings to gluten free diet. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Portugal | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 2% |
Spain | 1 | 2% |
United States | 1 | 2% |
Unknown | 60 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 12 | 19% |
Student > Master | 8 | 13% |
Researcher | 8 | 13% |
Other | 7 | 11% |
Student > Doctoral Student | 4 | 6% |
Other | 5 | 8% |
Unknown | 19 | 30% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 21 | 33% |
Agricultural and Biological Sciences | 5 | 8% |
Nursing and Health Professions | 4 | 6% |
Immunology and Microbiology | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Other | 4 | 6% |
Unknown | 23 | 37% |