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The miRNAome of the postpartum dairy cow liver in negative energy balance

Overview of attention for article published in BMC Genomics, April 2014
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Title
The miRNAome of the postpartum dairy cow liver in negative energy balance
Published in
BMC Genomics, April 2014
DOI 10.1186/1471-2164-15-279
Pubmed ID
Authors

Attia Fatima, David J Lynn, Padraic O’Boyle, Cathal Seoighe, Dermot Morris

Abstract

Negative energy balance (NEB) is an altered metabolic state in high yielding cows that occurs during the first few weeks postpartum when energy demands for lactation and maintenance exceed the energy supply from dietary intake. NEB can, in turn, lead to metabolic disorders and to reduced fertility. Alterations in the expression of more than 700 hepatic genes have previously been reported in a study of NEB in postpartum dairy cows. miRNAs (microRNA) are known to mediate many alterations in gene expression post transcriptionally. To study the hepatic miRNA content of postpartum dairy cows, including their overall abundance and differential expression, in mild NEB (MNEB) and severe NEB (SNEB), short read RNA sequencing was carried out. To identify putative targets of differentially expressed miRNAs among differentially expressed hepatic genes reported previously in dairy cows in SNEB computational target identification was employed.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 23%
Student > Master 5 14%
Student > Ph. D. Student 5 14%
Student > Doctoral Student 3 9%
Lecturer 2 6%
Other 5 14%
Unknown 7 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 51%
Veterinary Science and Veterinary Medicine 3 9%
Biochemistry, Genetics and Molecular Biology 3 9%
Medicine and Dentistry 2 6%
Mathematics 1 3%
Other 2 6%
Unknown 6 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2014.
All research outputs
#20,228,193
of 22,753,345 outputs
Outputs from BMC Genomics
#9,262
of 10,636 outputs
Outputs of similar age
#193,810
of 226,854 outputs
Outputs of similar age from BMC Genomics
#140
of 167 outputs
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