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Nicotinic Acid Activates the Capsaicin Receptor TRPV1

Overview of attention for article published in Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire), March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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18 X users
reddit
1 Redditor

Citations

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34 Dimensions

Readers on

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32 Mendeley
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Title
Nicotinic Acid Activates the Capsaicin Receptor TRPV1
Published in
Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire), March 2014
DOI 10.1161/atvbaha.113.303346
Pubmed ID
Authors

Linlin Ma, Bo Hyun Lee, Rongrong Mao, Anping Cai, Yunfang Jia, Heather Clifton, Saul Schaefer, Lin Xu, Jie Zheng

Abstract

Nicotinic acid (also known as niacin or vitamin B3), widely used to treat dyslipidemias, represents an effective and safe means to reduce the risk of mortality from cardiovascular disease. Nonetheless, a substantial fraction of patients discontinue treatment because of a strong side effect of cutaneous vasodilation, commonly termed flushing. In the present study, we tested the hypothesis that nicotinic acid causes flushing partially by activating the capsaicin receptor TRPV1, a polymodal cellular sensor that mediates the flushing response on consumption of spicy food.

X Demographics

X Demographics

The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Student > Master 5 16%
Other 3 9%
Student > Bachelor 3 9%
Researcher 3 9%
Other 4 13%
Unknown 8 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 19%
Biochemistry, Genetics and Molecular Biology 4 13%
Medicine and Dentistry 4 13%
Nursing and Health Professions 2 6%
Engineering 2 6%
Other 4 13%
Unknown 10 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2022.
All research outputs
#3,323,014
of 25,374,917 outputs
Outputs from Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire)
#735
of 6,064 outputs
Outputs of similar age
#32,177
of 238,073 outputs
Outputs of similar age from Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire)
#9
of 58 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,064 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,073 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.