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New roles for old enzymes: killer caspases as the engine of cell behavior changes

Overview of attention for article published in Frontiers in Physiology, April 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

news
1 news outlet
twitter
5 X users
video
1 YouTube creator

Citations

dimensions_citation
74 Dimensions

Readers on

mendeley
110 Mendeley
citeulike
1 CiteULike
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Title
New roles for old enzymes: killer caspases as the engine of cell behavior changes
Published in
Frontiers in Physiology, April 2014
DOI 10.3389/fphys.2014.00149
Pubmed ID
Authors

Patrick F. Connolly, Richard Jäger, Howard O. Fearnhead

Abstract

It has become increasingly clear that caspases, far from being merely cell death effectors, have a much wider range of functions within the cell. These functions are as diverse as signal transduction and cytoskeletal remodeling, and caspases are now known to have an essential role in cell proliferation, migration, and differentiation. There is also evidence that apoptotic cells themselves can direct the behavior of nearby cells through the caspase-dependent secretion of paracrine signaling factors. In some processes, including the differentiation of skeletal muscle myoblasts, both caspase activation in differentiating cells as well as signaling from apoptotic cells has been reported. Here, we review the non-apoptotic outcomes of caspase activity in a range of different model systems and attempt to integrate this knowledge.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Portugal 1 <1%
Unknown 107 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 31%
Student > Master 19 17%
Researcher 17 15%
Lecturer 4 4%
Professor 4 4%
Other 9 8%
Unknown 23 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 36 33%
Biochemistry, Genetics and Molecular Biology 27 25%
Medicine and Dentistry 11 10%
Neuroscience 8 7%
Sports and Recreations 1 <1%
Other 3 3%
Unknown 24 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2022.
All research outputs
#2,711,267
of 23,515,383 outputs
Outputs from Frontiers in Physiology
#1,431
of 14,233 outputs
Outputs of similar age
#25,117
of 204,956 outputs
Outputs of similar age from Frontiers in Physiology
#20
of 108 outputs
Altmetric has tracked 23,515,383 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,233 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 204,956 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 108 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.