| Title |
Autoimmunity: An Underlying Factor in the Pathogenesis of Hypertension
|
|---|---|
| Published in |
Current Hypertension Reports, February 2014
|
| DOI | 10.1007/s11906-014-0424-1 |
| Pubmed ID | |
| Authors |
Keisa W. Mathis, Hanna J. Broome, Michael J. Ryan |
| Abstract |
One in every three adults in the United States has hypertension, and the underlying cause of most of these cases is unknown. Therefore, it is imperative to continue the study of mechanisms involved in the pathogenesis of hypertension. Decades ago, studies speculated that elements of an autoimmune response were associated with the development of hypertension based, in part, on the presence of circulating autoantibodies in hypertensive patients. In the past decade, a growing number of studies have been published supporting the concept that self-antigens and the subsequent activation of the adaptive immune system promote the development of hypertension. This manuscript will provide a brief review of the evidence supporting a role for the immune system in the development of hypertension, studies that implicate both cell-mediated and humoral immunity, and the relevance of understanding blood pressure control in an autoimmune disease model with hypertension. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 15% |
| United Kingdom | 1 | 8% |
| Unknown | 10 | 77% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 23% |
| Student > Ph. D. Student | 3 | 23% |
| Student > Bachelor | 2 | 15% |
| Other | 1 | 8% |
| Student > Doctoral Student | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 3 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 46% |
| Agricultural and Biological Sciences | 2 | 15% |
| Nursing and Health Professions | 1 | 8% |
| Unknown | 4 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2014.
All research outputs
#17,719,891
of 22,754,104 outputs
Outputs from Current Hypertension Reports
#524
of 732 outputs
Outputs of similar age
#156,642
of 224,140 outputs
Outputs of similar age from Current Hypertension Reports
#6
of 14 outputs
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So far Altmetric has tracked 732 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
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We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.