Title |
In Utero Exposure to Selective Serotonin Reuptake Inhibitors and Risk for Autism Spectrum Disorder
|
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Published in |
Journal of Autism and Developmental Disorders, May 2014
|
DOI | 10.1007/s10803-014-2128-4 |
Pubmed ID | |
Authors |
Nicole B. Gidaya, Brian K. Lee, Igor Burstyn, Michael Yudell, Erik L. Mortensen, Craig J. Newschaffer |
Abstract |
We investigated whether there is an association between increased risk for autism spectrum disorders (ASD) and selective serotonin reuptake inhibitors (SSRIs) used during pregnancy. This study used Denmark's health and population registers to obtain information regarding prescription drugs, ASD diagnosis, and health and socioeconomic status. There were 1.5 % of cases and 0.7 % of controls exposed to SSRIs during the pregnancy period, and higher effect estimates observed with longer use. We found evidence that in utero exposure to SSRIs increases a child's risk associated with ASD. These results, while adding to the limited knowledge on prenatal pharmacological exposures as potential ASD risk factors, need to be balanced against the benefits of indicated medication use by pregnant mothers. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 25% |
United Kingdom | 2 | 17% |
Canada | 2 | 17% |
Argentina | 1 | 8% |
Unknown | 4 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 9 | 75% |
Practitioners (doctors, other healthcare professionals) | 2 | 17% |
Scientists | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 2% |
Unknown | 191 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 31 | 16% |
Student > Master | 29 | 15% |
Student > Ph. D. Student | 22 | 11% |
Student > Bachelor | 20 | 10% |
Student > Doctoral Student | 18 | 9% |
Other | 31 | 16% |
Unknown | 44 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 43 | 22% |
Psychology | 36 | 18% |
Neuroscience | 13 | 7% |
Social Sciences | 11 | 6% |
Agricultural and Biological Sciences | 8 | 4% |
Other | 33 | 17% |
Unknown | 51 | 26% |