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Potential impact of human mitochondrial replacement on global policy regarding germline gene modification

Overview of attention for article published in Reproductive BioMedicine Online, April 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

blogs
1 blog
twitter
8 X users
wikipedia
1 Wikipedia page

Citations

dimensions_citation
57 Dimensions

Readers on

mendeley
124 Mendeley
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Title
Potential impact of human mitochondrial replacement on global policy regarding germline gene modification
Published in
Reproductive BioMedicine Online, April 2014
DOI 10.1016/j.rbmo.2014.04.001
Pubmed ID
Authors

Tetsuya Ishii

Abstract

Previous discussions regarding human germline gene modification led to a global consensus that no germline should undergo genetic modification. However, the UK Human Fertilisation and Embryology Authority, having conducted at the UK Government's request a scientific review and a wide public consultation, provided advice to the Government on the pros and cons of Parliament's lifting a ban on altering mitochondrial DNA content of human oocytes and embryos, so as to permit the prevention of maternal transmission of mitochondrial diseases. In this commentary, relevant ethical and biomedical issues are examined and requirements for proceeding with this novel procedure are suggested. Additionally, potentially significant impacts of the UK legalization on global policy concerning germline gene modification are discussed in the context of recent advances in genome-editing technology. It is concluded that international harmonization is needed, as well as further ethical and practical consideration, prior to the legalization of human mitochondrial replacement.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Nigeria 1 <1%
Unknown 123 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 39 31%
Student > Master 16 13%
Student > Ph. D. Student 8 6%
Student > Doctoral Student 8 6%
Researcher 7 6%
Other 21 17%
Unknown 25 20%
Readers by discipline Count As %
Medicine and Dentistry 22 18%
Biochemistry, Genetics and Molecular Biology 21 17%
Agricultural and Biological Sciences 20 16%
Philosophy 6 5%
Arts and Humanities 5 4%
Other 22 18%
Unknown 28 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2017.
All research outputs
#2,367,796
of 25,374,917 outputs
Outputs from Reproductive BioMedicine Online
#214
of 2,422 outputs
Outputs of similar age
#23,277
of 241,061 outputs
Outputs of similar age from Reproductive BioMedicine Online
#2
of 32 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,422 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,061 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.