Title |
Extracellular vesicle-mediated bone metabolism in the bone microenvironment
|
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Published in |
Journal of Bone and Mineral Metabolism, August 2017
|
DOI | 10.1007/s00774-017-0860-5 |
Pubmed ID | |
Authors |
Qi Li, Qiu-Ping Huang, Yi-Lin Wang, Qing-Sheng Huang |
Abstract |
Extracellular vesicles (EVs) are phospholipid membrane-enclosed entities containing specific proteins, RNA, miRNA, and lncRNA. EVs are released by various cells and play a vital role in cell communication by transferring their contents from the host cells to the recipient cells. The role of EVs has been characterized in a wide range of physiological and pathophysiological processes. In this context, we highlight recent advances in our understanding of the regulatory effects of EVs, with a focus on bone metabolism and the bone microenvironment. The roles of EVs in cell communication among bone-related cells, stem cells, tumor cells, and other cells under physiological or pathological conditions are also discussed. In addition, promising applications for EVs in treating bone-related diseases are proposed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 24% |
Student > Master | 12 | 24% |
Student > Bachelor | 3 | 6% |
Student > Doctoral Student | 2 | 4% |
Lecturer | 2 | 4% |
Other | 8 | 16% |
Unknown | 11 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 14 | 28% |
Medicine and Dentistry | 10 | 20% |
Engineering | 4 | 8% |
Agricultural and Biological Sciences | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Other | 6 | 12% |
Unknown | 12 | 24% |