| Title |
Risk factors associated with the occurrence of distal radius fractures in Japanese patients with rheumatoid arthritis: a prospective observational cohort study
|
|---|---|
| Published in |
Clinical Rheumatology, November 2013
|
| DOI | 10.1007/s10067-013-2415-z |
| Pubmed ID | |
| Authors |
Kensuke Ochi, Yuki Go, Takefumi Furuya, Katsunori Ikari, Atsuo Taniguchi, Hisashi Yamanaka, Shigeki Momohara |
| Abstract |
The aims of this study were to evaluate the association between potential risk factors and the occurrence of distal radius fractures in Japanese patients with rheumatoid arthritis (RA). A total of 9,987 patients (82.0 % female; mean age, 55.7 years) with RA were enrolled in a prospective, observational study from 2000 to 2011. Self-reported distal radius fractures were verified using patient medical records. Cox proportional hazards models were used to analyze independent contributions of various risk factors to distal radius fracture occurrence. During a mean follow-up of 5.7 years, 139 patients reported 153 distal radius fractures. Among these patients, 85 distal radius fractures following minor trauma in 85 patients (6 men, 79 women) were verified with medical records. Female gender (hazard ratio [HR], 2.96; 95 % confidence interval [CI], 1.18-7.45; P = 0.021), age (per 10 years, HR 1.55; 95 % CI, 1.24-1.95, P = 0.00016), body mass index (BMI) (per 1 kg/m(2), HR, 1.11; 95 % CI, 1.03-1.19; P = 0.0034), daily prednisolone dose (per milligram per day, HR, 1.10; 95 % CI, 1.05-1.16; P = 0.00015), and physician global visual analog scale (0-10 cm, HR, 0.98; 95 % CI, 0.96-1.00; P = 0.034) were significantly associated with the occurrence of distal radius fractures in Japanese patients with RA. A reduction in the daily prednisolone dose, together with the prevention of falls in female patients of advanced age with RA and a high BMI may be important in preventing distal radius fractures. |
Mendeley readers
The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 39 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor | 4 | 10% |
| Student > Master | 4 | 10% |
| Researcher | 4 | 10% |
| Other | 4 | 10% |
| Student > Bachelor | 3 | 8% |
| Other | 8 | 21% |
| Unknown | 12 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 31% |
| Nursing and Health Professions | 5 | 13% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Unspecified | 1 | 3% |
| Other | 3 | 8% |
| Unknown | 15 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2013.
All research outputs
#20,229,658
of 22,755,127 outputs
Outputs from Clinical Rheumatology
#2,616
of 2,988 outputs
Outputs of similar age
#187,845
of 215,674 outputs
Outputs of similar age from Clinical Rheumatology
#23
of 27 outputs
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