Title |
Uterine Artery Embolization for Symptomatic Adenomyosis: 7-Year Clinical Follow-up Using UFS-Qol Questionnaire
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Published in |
CardioVascular and Interventional Radiology, May 2017
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DOI | 10.1007/s00270-017-1686-1 |
Pubmed ID | |
Authors |
Annefleur M. de Bruijn, Marieke Smink, Wouter J. K. Hehenkamp, Robbert J. Nijenhuis, Albert J. Smeets, Focco Boekkooi, Paul J. H. M. Reuwer, Willem J. Van Rooij, Paul N. M. Lohle |
Abstract |
The purpose of this study was to assess clinical outcomes 7 years after uterine artery embolization (UAE) in the treatment of symptomatic adenomyosis. In this prospective cohort study, one specialized hospital in the Netherlands recruited patients with symptomatic adenomyosis or adenomyosis in combination with fibroids for UAE. The 7-year post-intervention outcomes were health-related quality of life (HRQOL), symptom severity scores (SSS), satisfaction, menopause and re-interventions. Twenty-nine patients with adenomyosis (15 with fibroids) were treated with UAE between September 2006 and January 2010. The 7-year questionnaire was mailed in November 2016. The mean follow-up was 95 months (SD 9.0) at a mean age of 50 (SD 5.4). Questionnaires were returned by 24/29 patients (83%). The remaining five patients were contacted through telephone. One of these patients was untraceable. Seven years after treatment 5 of 28 patients (18%) underwent a secondary hysterectomy. The HRQOL and SSS scores as measured by UFS-QOL at 3 months after UAE showed significant improvement of -57 points (score: 15) and +40 points (score: 91), respectively. These scores remained comparable stable up unto 7 years. The SSS showed a significant difference of 17 points (0-100) in favor of the adenomyosis in combination with fibroids group (p = 0.020). Menopause was reported by 10/28 patients (36%). Twenty-one of 29 (72%) patients declared to be at least fairly satisfied about UAE. After 7 years of follow-up, in 82% of UAE-treated patients with symptomatic adenomyosis a hysterectomy was avoided. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 8 | 26% |
United Kingdom | 5 | 16% |
Saudi Arabia | 3 | 10% |
Spain | 2 | 6% |
Greece | 1 | 3% |
Chile | 1 | 3% |
India | 1 | 3% |
Unknown | 10 | 32% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 15 | 48% |
Practitioners (doctors, other healthcare professionals) | 12 | 39% |
Science communicators (journalists, bloggers, editors) | 3 | 10% |
Scientists | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 61 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 8 | 13% |
Other | 6 | 10% |
Researcher | 5 | 8% |
Student > Bachelor | 4 | 7% |
Student > Master | 4 | 7% |
Other | 11 | 18% |
Unknown | 23 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 34% |
Nursing and Health Professions | 6 | 10% |
Agricultural and Biological Sciences | 4 | 7% |
Mathematics | 1 | 2% |
Immunology and Microbiology | 1 | 2% |
Other | 3 | 5% |
Unknown | 25 | 41% |