| Title |
The Evolution of Electrospray Generated Droplets is Not Affected by Ionization Mode
|
|---|---|
| Published in |
Journal of the American Society for Mass Spectrometry, July 2017
|
| DOI | 10.1007/s13361-017-1737-5 |
| Pubmed ID | |
| Authors |
Piia Liigand, Agnes Heering (Suu), Karl Kaupmees, Ivo Leito, Marion Girod, Rodolphe Antoine, Anneli Kruve |
| Abstract |
Ionization efficiency and mechanism in ESI is strongly affected by the properties of mobile phase. The use of mobile-phase properties to accurately describe droplets in ESI source is convenient but may be inadequate as the composition of the droplets is changing in the plume due to electrochemical reactions occurring in the needle tip as well as continuous drying and fission of droplets. Presently, there is paucity of research on the effect of the polarity of the ESI mode on mobile phase composition in the droplets. In this paper, the change in the organic solvent content, pH, and droplet size are studied in the ESI plume in both ESI+ and ESI- ionization mode. We introduce a rigorous way - the absolute pH (pHabs(H)2(O)) - to describe pH change in the plume that takes into account organic solvent content in the mobile phase. pHabs(H)2(O) enables comparing acidities of ESI droplets with different organic solvent contents. The results are surprisingly similar for both ionization modes, indicating that the dynamics of the change of mobile-phase properties is independent from the ESI mode used. This allows us to conclude that the evolution of ESI droplets first of all proceeds via the evaporation of the organic modifier and to a lesser extent via fission of smaller droplets from parent droplets. Secondly, our study shows that qualitative findings related to the ESI process obtained on the ESI+ mode can almost directly be applied also in the ESI- mode. Graphical Abstract ᅟ. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 3 | 33% |
| Sweden | 1 | 11% |
| United States | 1 | 11% |
| Unknown | 4 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 56% |
| Scientists | 3 | 33% |
| Science communicators (journalists, bloggers, editors) | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 50 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 26% |
| Researcher | 12 | 24% |
| Professor | 5 | 10% |
| Other | 4 | 8% |
| Student > Master | 4 | 8% |
| Other | 4 | 8% |
| Unknown | 8 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 24 | 48% |
| Engineering | 4 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 4% |
| Physics and Astronomy | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 11 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2017.
All research outputs
#7,150,392
of 25,382,440 outputs
Outputs from Journal of the American Society for Mass Spectrometry
#960
of 3,835 outputs
Outputs of similar age
#105,308
of 327,041 outputs
Outputs of similar age from Journal of the American Society for Mass Spectrometry
#12
of 76 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 3,835 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,041 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.