Title |
Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions
|
---|---|
Published in |
BMC Cancer, April 2010
|
DOI | 10.1186/1471-2407-10-156 |
Pubmed ID | |
Authors |
Giovanni P Burrai, Sulma I Mohammed, Margaret A Miller, Vincenzo Marras, Salvatore Pirino, Maria F Addis, Sergio Uzzau, Elisabetta Antuofermo |
Abstract |
Breast cancer is the most frequently diagnosed cancer in women. Intraepithelial lesions (IELs), such as usual ductal hyperplasia (UH), atypical ductal hyperplasia (ADH), and ductal carcinoma in situ (DCIS) are risk factors that predict a woman's chance of developing invasive breast cancer. Therefore, a comparative study that establishes an animal model of pre-invasive lesions is needed for the development of preventative measures and effective treatment for both mammary IELs and tumors. The purpose of this study was to characterize the histologic and molecular features of feline mammary IELs and compare them with those in women. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 2% |
Italy | 1 | 2% |
Unknown | 61 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 14 | 22% |
Student > Bachelor | 7 | 11% |
Student > Doctoral Student | 6 | 10% |
Student > Postgraduate | 5 | 8% |
Student > Ph. D. Student | 5 | 8% |
Other | 10 | 16% |
Unknown | 16 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 17 | 27% |
Medicine and Dentistry | 15 | 24% |
Agricultural and Biological Sciences | 6 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Economics, Econometrics and Finance | 1 | 2% |
Other | 0 | 0% |
Unknown | 21 | 33% |