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Increased levels of circulating CD34+ cells in neovascular age-related macular degeneration: relation with clinical and OCT features

Overview of attention for article published in European Journal of Ophthalmology, February 2018
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Title
Increased levels of circulating CD34+ cells in neovascular age-related macular degeneration: relation with clinical and OCT features
Published in
European Journal of Ophthalmology, February 2018
DOI 10.5301/ejo.5001012
Pubmed ID
Authors

Caner Kara, Pınar Ç. Özdal, Emrullah Beyazyıldız, Nurgül E. Özcan, Mehmet Y. Teke, Gülden Vural, Faruk Öztürk

Abstract

To investigate the levels of circulating CD34+ stem cells in patients with neovascular type age-related macular degeneration (AMD) and its relation with clinical and optical coherence tomography (OCT) findings. The study consisted of 55 patients: 28 patients (18 male and 10 female) with neovascular type AMD as a study group and 27 patients (12 male and 15 female) scheduled for cataract surgery as a control group. The level of CD34+ stem cells was measured by flow cytometry. Demographic and clinical data were recorded. The mean ages of patients in the study and control groups were 71 ± 8 and 68 ± 6 years, respectively. There was no statistically significant difference in terms of age, sex, or systemic disease association between study and control groups. However, smoking status was significantly higher in the study group (67.9% vs 37.0%; p = 0.02). Stem cell levels were significantly higher in the study group (1.5 ± 0.9 vs 0.5 ± 0.3; p<0.001), but there was no relation between stem cell levels and clinical and OCT findings. Increased circulating CD34+ stem cell levels were observed in patients with choroidal neovascular membrane associated with AMD, but no significant relation was found between cell levels and clinical and OCT findings.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 31%
Student > Master 3 23%
Lecturer 1 8%
Student > Doctoral Student 1 8%
Other 1 8%
Other 3 23%
Readers by discipline Count As %
Medicine and Dentistry 7 54%
Agricultural and Biological Sciences 3 23%
Nursing and Health Professions 1 8%
Unknown 2 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2017.
All research outputs
#18,566,650
of 22,996,001 outputs
Outputs from European Journal of Ophthalmology
#645
of 1,102 outputs
Outputs of similar age
#256,792
of 330,753 outputs
Outputs of similar age from European Journal of Ophthalmology
#182
of 203 outputs
Altmetric has tracked 22,996,001 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,102 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,753 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 203 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.