Title |
Improving Working Memory in Children with Attention-Deficit/Hyperactivity Disorder: The Separate and Combined Effects of Incentives and Stimulant Medication
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Published in |
Research on Child and Adolescent Psychopathology, April 2012
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DOI | 10.1007/s10802-012-9627-6 |
Pubmed ID | |
Authors |
Michael T. Strand, Larry W. Hawk, Michelle Bubnik, Keri Shiels, William E. Pelham, James G. Waxmonsky |
Abstract |
Working memory (WM) is considered a core deficit in Attention-Deficit/ Hyperactivity Disorder (ADHD), with numerous studies demonstrating impaired WM among children with ADHD. We tested the degree to which WM in children with ADHD was improved by performance-based incentives, an analog of behavioral intervention. In two studies, WM performance was assessed using a visuo-spatial n-back task. Study 1 compared children (ages 9-12 years) with ADHD-Combined type (n = 24) to a group of typically developing (TD) children (n = 32). Study 1 replicated WM deficits among children with ADHD. Incentives improved WM, particularly among children with ADHD. The provision of incentives reduced the ADHD-control group difference by approximately half but did not normalize WM. Study 2 examined the separate and combined effects of incentives and stimulant medication among 17 children with ADHD-Combined type. Both incentives and a moderate dose of long-acting methylphenidate (MPH; ~0.3 mg/kg t.i.d. equivalent) robustly improved WM relative to the no-incentive, placebo condition. The combination of incentives and medication improved WM significantly more than either incentives or MPH alone. These studies indicate that contingencies markedly improve WM among children with ADHD-Combined type, with effect sizes comparable to a moderate dose of stimulant medication. More broadly, this work calls attention to the role of motivation in studying cognitive deficits in ADHD and in testing multifactorial models of ADHD. |
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Geographical breakdown
Country | Count | As % |
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United States | 2 | 1% |
Netherlands | 2 | 1% |
Germany | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 151 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 33 | 21% |
Student > Master | 28 | 18% |
Student > Bachelor | 20 | 13% |
Researcher | 11 | 7% |
Student > Doctoral Student | 10 | 6% |
Other | 28 | 18% |
Unknown | 27 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 64 | 41% |
Social Sciences | 19 | 12% |
Medicine and Dentistry | 12 | 8% |
Agricultural and Biological Sciences | 6 | 4% |
Nursing and Health Professions | 5 | 3% |
Other | 19 | 12% |
Unknown | 32 | 20% |