| Title |
In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer’s disease
|
|---|---|
| Published in |
European Journal of Nuclear Medicine and Molecular Imaging, September 2010
|
| DOI | 10.1007/s00259-010-1612-0 |
| Pubmed ID | |
| Authors |
Masamichi Yokokura, Norio Mori, Shunsuke Yagi, Etsuji Yoshikawa, Mitsuru Kikuchi, Yujiro Yoshihara, Tomoyasu Wakuda, Genichi Sugihara, Kiyokazu Takebayashi, Shiro Suda, Yasuhide Iwata, Takatoshi Ueki, Kenji J. Tsuchiya, Katsuaki Suzuki, Kazuhiko Nakamura, Yasuomi Ouchi |
| Abstract |
Amyloid β protein (Aβ) is known as a pathological substance in Alzheimer's disease (AD) and is assumed to coexist with a degree of activated microglia in the brain. However, it remains unclear whether these two events occur in parallel with characteristic hypometabolism in AD in vivo. The purpose of the present study was to clarify the in vivo relationship between Aβ accumulation and neuroinflammation in those specific brain regions in early AD. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Netherlands | 1 | <1% |
| United Kingdom | 1 | <1% |
| France | 1 | <1% |
| Japan | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 121 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 30 | 23% |
| Student > Ph. D. Student | 19 | 15% |
| Student > Master | 11 | 9% |
| Student > Doctoral Student | 11 | 9% |
| Student > Bachelor | 11 | 9% |
| Other | 31 | 24% |
| Unknown | 16 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 35 | 27% |
| Neuroscience | 26 | 20% |
| Agricultural and Biological Sciences | 16 | 12% |
| Biochemistry, Genetics and Molecular Biology | 7 | 5% |
| Psychology | 7 | 5% |
| Other | 10 | 8% |
| Unknown | 28 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2012.
All research outputs
#14,882,733
of 23,806,312 outputs
Outputs from European Journal of Nuclear Medicine and Molecular Imaging
#1,782
of 3,083 outputs
Outputs of similar age
#68,911
of 87,314 outputs
Outputs of similar age from European Journal of Nuclear Medicine and Molecular Imaging
#12
of 12 outputs
Altmetric has tracked 23,806,312 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,083 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
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We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.