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Mendeley readers
Attention Score in Context
| Title |
Hydrogen Sulfide
|
|---|---|
| Published in |
Shock, November 2017
|
| DOI | 10.1097/shk.0000000000000894 |
| Pubmed ID | |
| Authors |
Amanda R. Jensen, Natalie A. Drucker, Sina Khaneki, Michael J. Ferkowicz, Mervin C. Yoder, Eric R. DeLeon, Kenneth R. Olson, Troy A. Markel |
| Abstract |
Hydrogen sulfide (H2S) is a novel signaling molecule most recently found to be of fundamental importance in cellular function as a regulator of apoptosis, inflammation, and perfusion. Mechanisms of endogenous H2S signaling are poorly understood, however, signal transmission is thought to occur via persulfidation at reactive cysteine residues on proteins. Although much has been discovered about how H2S is synthesized in the body, less is known about how it is metabolized. Recent studies have discovered a multitude of different targets for H2S therapy, including those related to protein modification, intracellular signaling, and ion channel depolarization. The most difficult part of studying hydrogen sulfide has been finding a way to accurately and reproducibly measure it. The purpose of this review is to: 1) elaborate on the biosynthesis and catabolism of H2S in the human body, 2) review current knowledge of the mechanisms of action of this gas in relation to ischemic injury, 3) define strategies for physiological measurement of H2S in biological systems, and 4) review potential novel therapies that use H2S for treatment. |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 3 | 14% |
| Researcher | 3 | 14% |
| Student > Postgraduate | 3 | 14% |
| Other | 2 | 9% |
| Professor > Associate Professor | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 9 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 18% |
| Nursing and Health Professions | 2 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 9% |
| Biochemistry, Genetics and Molecular Biology | 1 | 5% |
| Immunology and Microbiology | 1 | 5% |
| Other | 3 | 14% |
| Unknown | 9 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2017.
All research outputs
#20,442,790
of 22,997,544 outputs
Outputs from Shock
#2,845
of 3,107 outputs
Outputs of similar age
#286,786
of 329,099 outputs
Outputs of similar age from Shock
#18
of 22 outputs
Altmetric has tracked 22,997,544 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,107 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,099 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.