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Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis

Overview of attention for article published in Multiple Sclerosis Journal, May 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users
patent
1 patent

Citations

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59 Dimensions

Readers on

mendeley
64 Mendeley
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Title
Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis
Published in
Multiple Sclerosis Journal, May 2014
DOI 10.1177/1352458514536252
Pubmed ID
Authors

Michael P Pender, Peter A Csurhes, Casey Mm Pfluger, Scott R Burrows

Abstract

Patients with multiple sclerosis (MS) have a deficiency of circulating CD8(+) T cells, which might impair control of Epstein-Barr virus (EBV) and predispose to MS by allowing EBV-infected autoreactive B cells to accumulate in the central nervous system. Based on the expression of CD45RA and CD62L, CD4(+) T cells and CD8(+) T cells can be subdivided into four subsets with distinct homing and functional properties, namely: naïve, central memory, effector memory (EM) and effector memory re-expressing CD45RA (EMRA) cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Unknown 62 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 16%
Researcher 9 14%
Student > Doctoral Student 8 13%
Student > Bachelor 7 11%
Student > Master 6 9%
Other 11 17%
Unknown 13 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 17%
Medicine and Dentistry 10 16%
Immunology and Microbiology 8 13%
Biochemistry, Genetics and Molecular Biology 5 8%
Neuroscience 5 8%
Other 8 13%
Unknown 17 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2021.
All research outputs
#2,539,791
of 22,668,244 outputs
Outputs from Multiple Sclerosis Journal
#720
of 3,438 outputs
Outputs of similar age
#26,911
of 227,028 outputs
Outputs of similar age from Multiple Sclerosis Journal
#7
of 60 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,438 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,028 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.