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VAV3 mediates resistance to breast cancer endocrine therapy

Overview of attention for article published in Breast Cancer Research, May 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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4 X users
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2 patents

Citations

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29 Dimensions

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Title
VAV3 mediates resistance to breast cancer endocrine therapy
Published in
Breast Cancer Research, May 2014
DOI 10.1186/bcr3664
Pubmed ID
Authors

Helena Aguilar, Ander Urruticoechea, Pasi Halonen, Kazuma Kiyotani, Taisei Mushiroda, Xavier Barril, Jordi Serra-Musach, Abul Islam, Livia Caizzi, Luciano Di Croce, Ekaterina Nevedomskaya, Wilbert Zwart, Josefine Bostner, Elin Karlsson, Gizeh Pérez Tenorio, Tommy Fornander, Dennis C Sgroi, Rafael Garcia-Mata, Maurice PHM Jansen, Nadia García, Núria Bonifaci, Fina Climent, María Teresa Soler, Alejo Rodríguez-Vida, Miguel Gil, Joan Brunet, Griselda Martrat, Laia Gómez-Baldó, Ana I Extremera, Agnes Figueras, Josep Balart, Robert Clarke, Kerry L Burnstein, Kathryn E Carlson, John A Katzenellenbogen, Miguel Vizoso, Manel Esteller, Alberto Villanueva, Ana B Rodríguez-Peña, Xosé R Bustelo, Yusuke Nakamura, Hitoshi Zembutsu, Olle Stål, Roderick L Beijersbergen, Miguel Angel Pujana

Abstract

Endocrine therapies targeting cell proliferation and survival mediated by estrogen receptor α (ERα) are among the most effective systemic treatments for ERα-positive breast cancer. However, most tumors initially responsive to these therapies acquire resistance through mechanisms that involve ERα transcriptional regulatory plasticity. Herein we identify VAV3 as a critical component in this process.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 3 4%
United Kingdom 1 1%
Netherlands 1 1%
United States 1 1%
Unknown 74 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 15%
Student > Ph. D. Student 10 13%
Student > Master 8 10%
Professor 7 9%
Student > Bachelor 7 9%
Other 16 20%
Unknown 20 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 20%
Biochemistry, Genetics and Molecular Biology 14 18%
Medicine and Dentistry 13 16%
Computer Science 3 4%
Chemistry 3 4%
Other 8 10%
Unknown 23 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2023.
All research outputs
#5,378,711
of 25,373,627 outputs
Outputs from Breast Cancer Research
#635
of 2,052 outputs
Outputs of similar age
#49,609
of 241,291 outputs
Outputs of similar age from Breast Cancer Research
#8
of 35 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,291 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.