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Mendeley readers
Attention Score in Context
| Title |
The Truth about False Unicorn (Chamaelirium luteum): Total Synthesis of 23R,24S‐Chiograsterol B Defines the Structure and Stereochemistry of the Major Saponins from this Medicinal Herb
|
|---|---|
| Published in |
Chemistry - A European Journal, May 2011
|
| DOI | 10.1002/chem.201100503 |
| Pubmed ID | |
| Authors |
Nicholas J. Matovic, Julia M. U. Stuthe, Victoria L. Challinor, Paul V. Bernhardt, Reginald P. Lehmann, William Kitching, James J. De Voss |
| Abstract |
Chamaelirium luteum is used in traditional medicine systems and commercial botanical dietary supplements for the treatment of female reproductive health problems. Despite the wide use of this herb, only very limited phytochemical characterisation is available. Our investigation of C. luteum roots led to the isolation of two new steroidal saponins 1 and 2 that contain an unusual aglycone 3. The absolute configurations of these molecules were unable to be determined spectroscopically and thus the total synthesis of 3 was undertaken and achieved in 16 steps and 1.6 % overall yield from pregnenolone. The key step in the synthesis was the stereoselective installation of the side chain at C-17 and C-20, which employed anion-accelerated oxy-Cope methodology. The relative configuration of aglycone 3 was determined by X-ray crystallography of an advanced synthetic intermediate. The absolute configuration was based upon that of the pregnenolone-derived steroidal skeleton and determined to be 23R,24S. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Lebanon | 1 | 7% |
| Unknown | 13 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 50% |
| Researcher | 2 | 14% |
| Student > Bachelor | 1 | 7% |
| Student > Master | 1 | 7% |
| Lecturer | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 2 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 7 | 50% |
| Medicine and Dentistry | 2 | 14% |
| Sports and Recreations | 1 | 7% |
| Economics, Econometrics and Finance | 1 | 7% |
| Engineering | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 2 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2014.
All research outputs
#4,641,692
of 24,629,540 outputs
Outputs from Chemistry - A European Journal
#3,205
of 22,968 outputs
Outputs of similar age
#22,498
of 115,914 outputs
Outputs of similar age from Chemistry - A European Journal
#11
of 93 outputs
Altmetric has tracked 24,629,540 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,968 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 115,914 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.