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Tandem Reactions via Barton Esters with Intermolecular Addition and Vinyl Radical Substitution onto Indole

Overview of attention for article published in Journal of Organic Chemistry, May 2014
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Title
Tandem Reactions via Barton Esters with Intermolecular Addition and Vinyl Radical Substitution onto Indole
Published in
Journal of Organic Chemistry, May 2014
DOI 10.1021/jo5008543
Pubmed ID
Authors

Robert Coyle, Patrick McArdle, Fawaz Aldabbagh

Abstract

A one-pot initiator-free Barton ester decomposition with tandem radical addition onto alkyl propiolates or phenylacetylene with aromatic substitution of the resultant vinyl radical allows convenient access to new 9-substituted 6,7-dihydropyrido[1,2-a]indoles. Propyl radical cyclizations compete when forming the expanded 7,8-dihydro-6H-azepino[1,2-a]indole system. 2-Thiopyridinyl S-radical is incorporated into aromatic adducts when using unsubstituted indole-1-alkanoic acid precursors. X-ray crystallography on substitution products allows selectivity of the radical addition onto less reactive internal alkynes to be determined.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 33%
Student > Bachelor 1 11%
Other 1 11%
Student > Master 1 11%
Researcher 1 11%
Other 0 0%
Unknown 2 22%
Readers by discipline Count As %
Chemistry 7 78%
Unknown 2 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2014.
All research outputs
#20,657,128
of 25,377,790 outputs
Outputs from Journal of Organic Chemistry
#26,833
of 28,613 outputs
Outputs of similar age
#177,142
of 241,296 outputs
Outputs of similar age from Journal of Organic Chemistry
#93
of 122 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 28,613 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 2nd percentile – i.e., 2% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,296 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.