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Contribution of genetic variation to transgenerational inheritance of DNA methylation

Overview of attention for article published in Genome Biology, May 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

blogs
1 blog
twitter
139 X users
peer_reviews
1 peer review site
facebook
1 Facebook page
googleplus
3 Google+ users

Citations

dimensions_citation
231 Dimensions

Readers on

mendeley
255 Mendeley
citeulike
5 CiteULike
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Title
Contribution of genetic variation to transgenerational inheritance of DNA methylation
Published in
Genome Biology, May 2014
DOI 10.1186/gb-2014-15-5-r73
Pubmed ID
Authors

Allan F McRae, Joseph E Powell, Anjali K Henders, Lisa Bowdler, Gibran Hemani, Sonia Shah, Jodie N Painter, Nicholas G Martin, Peter M Visscher, Grant W Montgomery

Abstract

Despite the important role DNA methylation plays in transcriptional regulation, the transgenerational inheritance of DNA methylation is not well understood. The genetic heritability of DNA methylation has been estimated using twin pairs, although concern has been expressed whether the underlying assumption of equal common environmental effects are applicable due to intrauterine differences between monozygotic and dizygotic twins. We estimate the heritability of DNA methylation on peripheral blood leukocytes using Illumina HumanMethylation450 array using a family based sample of 614 people from 117 families, allowing comparison both within and across generations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 139 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 255 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 2%
Switzerland 2 <1%
Turkey 1 <1%
France 1 <1%
Germany 1 <1%
Canada 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
New Zealand 1 <1%
Other 0 0%
Unknown 242 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 75 29%
Researcher 66 26%
Student > Master 21 8%
Student > Doctoral Student 19 7%
Professor 12 5%
Other 40 16%
Unknown 22 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 106 42%
Biochemistry, Genetics and Molecular Biology 60 24%
Medicine and Dentistry 19 7%
Computer Science 10 4%
Psychology 10 4%
Other 21 8%
Unknown 29 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 91. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2017.
All research outputs
#468,394
of 25,374,917 outputs
Outputs from Genome Biology
#258
of 4,467 outputs
Outputs of similar age
#4,018
of 240,314 outputs
Outputs of similar age from Genome Biology
#2
of 39 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,314 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.