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The Factor Structure and Presentation of Depression Among HIV-Positive Adults in Uganda

Overview of attention for article published in AIDS and Behavior, May 2014
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Title
The Factor Structure and Presentation of Depression Among HIV-Positive Adults in Uganda
Published in
AIDS and Behavior, May 2014
DOI 10.1007/s10461-014-0796-x
Pubmed ID
Authors

Christina Psaros, Jessica E. Haberer, Yap Boum, Alexander C. Tsai, Jeffrey N. Martin, Peter W. Hunt, David R. Bangsberg, Steven A. Safren

Abstract

Depression is one of the most prevalent psychiatric comorbidities of HIV and one of the greatest barriers to HIV self-care and adherence. Despite this, little consensus exists on how to best measure depression among people living with HIV/AIDS (PLWHA) in African settings. Measurement of depression among PLWHA may be confounded by somatic symptoms. Some research recommends excluding these items to enhance measurement validity; sensitivity may be lost with this approach. We sought to characterize depression among a cohort (N = 453) of PLWHA initiating antiretroviral therapy in Uganda via factor analysis of a widely used measure of depression, the Hopkins Symptom Checklist (HSCLD). Common factor analysis was performed, associations between HSCLD and the Mental Health subscale of the Medical Outcomes Study HIV (MOS-HIV) estimated, and a Cronbach's alpha calculated to examine validity. Factor analysis yielded two factors: (1) somatic-cognitive symptoms and (2) behavioral disengagement. Persons with more versus less advanced disease (CD4 cell count of ≤200 cells/mm(3)) showed no statistically significant differences in depression scores (1.7 vs. 1.7, P ≥ 0.5). Both factors were significantly associated with the MOS-HIV (P < .01). Factor one was highly reliable (α = .81); factor two had only modest reliability (α = .65). Somatic-cognitive symptoms of depression and disengagement from life's activities appear to be distinct components of depression in this sample. Consideration of somatic items may be valuable in identifying depression in this setting.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Tanzania, United Republic of 1 <1%
Unknown 124 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 24 19%
Student > Ph. D. Student 14 11%
Researcher 12 10%
Student > Bachelor 11 9%
Lecturer 8 6%
Other 25 20%
Unknown 31 25%
Readers by discipline Count As %
Medicine and Dentistry 36 29%
Nursing and Health Professions 17 14%
Psychology 10 8%
Social Sciences 8 6%
Agricultural and Biological Sciences 3 2%
Other 16 13%
Unknown 35 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2014.
All research outputs
#21,186,729
of 23,849,058 outputs
Outputs from AIDS and Behavior
#3,266
of 3,566 outputs
Outputs of similar age
#194,385
of 228,329 outputs
Outputs of similar age from AIDS and Behavior
#56
of 67 outputs
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