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Scabies Mites Alter the Skin Microbiome and Promote Growth of Opportunistic Pathogens in a Porcine Model

Overview of attention for article published in PLoS Neglected Tropical Diseases, May 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Citations

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69 Dimensions

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117 Mendeley
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Title
Scabies Mites Alter the Skin Microbiome and Promote Growth of Opportunistic Pathogens in a Porcine Model
Published in
PLoS Neglected Tropical Diseases, May 2014
DOI 10.1371/journal.pntd.0002897
Pubmed ID
Authors

Pearl M. Swe, Martha Zakrzewski, Andrew Kelly, Lutz Krause, Katja Fischer

Abstract

The resident skin microbiota plays an important role in restricting pathogenic bacteria, thereby protecting the host. Scabies mites (Sarcoptes scabiei) are thought to promote bacterial infections by breaching the skin barrier and excreting molecules that inhibit host innate immune responses. Epidemiological studies in humans confirm increased incidence of impetigo, generally caused by Staphylococcus aureus and Streptococcus pyogenes, secondary to the epidermal infestation with the parasitic mite. It is therefore possible that mite infestation could alter the healthy skin microbiota making way for the opportunistic pathogens. A longitudinal study to test this hypothesis in humans is near impossible due to ethical reasons. In a porcine model we generated scabies infestations closely resembling the disease manifestation in humans and investigated the scabies associated changes in the skin microbiota over the course of a mite infestation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 <1%
Germany 1 <1%
Canada 1 <1%
Unknown 114 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 15%
Researcher 16 14%
Student > Bachelor 12 10%
Student > Master 11 9%
Other 7 6%
Other 29 25%
Unknown 24 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 26%
Medicine and Dentistry 27 23%
Biochemistry, Genetics and Molecular Biology 12 10%
Veterinary Science and Veterinary Medicine 5 4%
Immunology and Microbiology 4 3%
Other 11 9%
Unknown 28 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2024.
All research outputs
#5,447,195
of 25,377,790 outputs
Outputs from PLoS Neglected Tropical Diseases
#3,430
of 9,377 outputs
Outputs of similar age
#49,878
of 240,314 outputs
Outputs of similar age from PLoS Neglected Tropical Diseases
#50
of 171 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,377 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,314 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 171 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.