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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Rapid, low-cost and instrument-free CD4+ cell counting for HIV diagnostics in resource-poor settings
|
|---|---|
| Published in |
Lab on a Chip - Miniaturisation for Chemistry & Biology, January 2014
|
| DOI | 10.1039/c4lc00264d |
| Pubmed ID | |
| Authors |
Macdara T. Glynn, David J. Kinahan, Jens Ducrée |
| Abstract |
We present a novel, user-friendly and widely autonomous point-of-care diagnostic to enable HIV monitoring in resource-poor regions where the current pandemic is most prevalent. To specifically isolate magnetically tagged CD4+ cells directly from patient blood, the low-cost and disposable microfluidic chip operates by dual-force CD4+ cell magnetophoresis; whereby the interplay of flow and magnetic fields governs the trajectory of target cells depending on whether the cell binds to a magnetic microbead. Instrument-free pumping is implemented by a finger-actuated elastic membrane; tagged beads are laterally deflected by a small and re-useable permanent magnet. The single-depth and monolithic microfluidic structure can easily be fabricated in a single casting step. After their magnetophoretic isolation from whole blood, estimation of CD4+ cell concentrations is then measured by bright-field inspection of the capture chamber. In addition, an optional fluorescence measurement can be used for confirmation of the bright-field result if required. On-chip CD4+ estimation produces a linear response over the full range of medically relevant CD4+ cell concentrations. Our technology combines high-efficiency capture (93.0 ± 3.3%) and cell enumeration. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Korea, Republic of | 1 | 1% |
| Unknown | 68 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 23% |
| Researcher | 16 | 23% |
| Student > Master | 11 | 16% |
| Other | 3 | 4% |
| Student > Bachelor | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 13 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 20 | 29% |
| Agricultural and Biological Sciences | 8 | 12% |
| Chemistry | 6 | 9% |
| Physics and Astronomy | 4 | 6% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Other | 12 | 17% |
| Unknown | 16 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2022.
All research outputs
#7,129,834
of 25,613,746 outputs
Outputs from Lab on a Chip - Miniaturisation for Chemistry & Biology
#2,278
of 5,965 outputs
Outputs of similar age
#76,960
of 320,581 outputs
Outputs of similar age from Lab on a Chip - Miniaturisation for Chemistry & Biology
#135
of 358 outputs
Altmetric has tracked 25,613,746 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 5,965 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,581 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 358 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.