Title |
The roles of viruses in brain tumor initiation and oncomodulation
|
---|---|
Published in |
Journal of Neuro-Oncology, July 2011
|
DOI | 10.1007/s11060-011-0658-6 |
Pubmed ID | |
Authors |
Alexander Kofman, Lucasz Marcinkiewicz, Evan Dupart, Anton Lyshchev, Boris Martynov, Anatolii Ryndin, Elena Kotelevskaya, Jay Brown, David Schiff, Roger Abounader |
Abstract |
While some avian retroviruses have been shown to induce gliomas in animal models, human herpesviruses, specifically, the most extensively studied cytomegalovirus, and the much less studied roseolovirus HHV-6, and Herpes simplex viruses 1 and 2, currently attract more and more attention as possible contributing or initiating factors in the development of human brain tumors. The aim of this review is to summarize and highlight the most provoking findings indicating a potential causative link between brain tumors, specifically malignant gliomas, and viruses in the context of the concepts of viral oncomodulation and the tumor stem cell origin. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 53 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 13% |
Student > Master | 7 | 13% |
Student > Ph. D. Student | 6 | 11% |
Other | 5 | 9% |
Student > Bachelor | 5 | 9% |
Other | 16 | 30% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 40% |
Biochemistry, Genetics and Molecular Biology | 11 | 21% |
Agricultural and Biological Sciences | 8 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Unspecified | 1 | 2% |
Other | 4 | 8% |
Unknown | 7 | 13% |