| Title |
Anxiety traits associated with a polymorphism in the serotonin transporter gene regulatory region in the Japanese
|
|---|---|
| Published in |
Journal of Human Genetics, January 1999
|
| DOI | 10.1007/s100380050098 |
| Pubmed ID | |
| Authors |
Fumiyo Murakami, T. Shimomura, Kazuhiko Kotani, Shiro Ikawa, Eiji Nanba, Kaori Adachi |
| Abstract |
We determined polymorphism in the serotonin (5-HT) transporter gene-linked polymorphic region (5-HTTLPR) in 501 healthy Japanese, individuals, using the polymerase chain reaction of Lesch et al., with minor modifications. The distribution of allele frequencies was determined and found to differ from that in Caucasians. We also investigated the relationship of polymorphism in 5-HTTLPR to anxiety traits, by having 189 of the 501 subjects complete a self-rating questionnaire for anxiety and depression. Subjects with the short/short (s/s) genotype had significantly higher anxiety scores than those with the long/long (l/l) or l/s genotype. It is suggested that populations with the s/s genotype of 5-HTTLPR have stronger anxiety-related personality traits than those with the 1 allele. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 15% |
| Unknown | 11 | 85% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Spain | 1 | 2% |
| India | 1 | 2% |
| Unknown | 56 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 19% |
| Student > Master | 9 | 15% |
| Student > Ph. D. Student | 8 | 14% |
| Student > Bachelor | 7 | 12% |
| Student > Doctoral Student | 3 | 5% |
| Other | 10 | 17% |
| Unknown | 11 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 25% |
| Psychology | 12 | 20% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Social Sciences | 4 | 7% |
| Agricultural and Biological Sciences | 3 | 5% |
| Other | 6 | 10% |
| Unknown | 15 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2024.
All research outputs
#2,972,217
of 25,175,727 outputs
Outputs from Journal of Human Genetics
#169
of 1,741 outputs
Outputs of similar age
#4,399
of 103,622 outputs
Outputs of similar age from Journal of Human Genetics
#1
of 13 outputs
Altmetric has tracked 25,175,727 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,741 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,622 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.