Title |
Therapy of Genetic Disorders: Novel Therapies for Duchenne Muscular Dystrophy
|
---|---|
Published in |
Current Pediatrics Reports, March 2014
|
DOI | 10.1007/s40124-014-0044-x |
Pubmed ID | |
Authors |
Jane T. Seto, Niclas E. Bengtsson, Jeffrey S. Chamberlain |
Abstract |
Duchenne muscular dystrophy (DMD) is an inherited, progressive muscle wasting disorder caused by mutations in the dystrophin gene. An increasing variety of approaches are moving towards clinical testing that all aim to restore dystrophin production and to enhance or preserve muscle mass. Gene therapy methods are being developed to replace the defective dystrophin gene or induce dystrophin production from mutant genes. Stem cell approaches are being developed to replace lost muscle cells while also bringing in new dystrophin genes. This review summarizes recent progress in the field with an emphasis on clinical applications. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 25% |
United States | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 50% |
Scientists | 1 | 25% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 57 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 19 | 32% |
Student > Ph. D. Student | 6 | 10% |
Student > Master | 6 | 10% |
Researcher | 4 | 7% |
Professor | 4 | 7% |
Other | 5 | 8% |
Unknown | 15 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 19 | 32% |
Biochemistry, Genetics and Molecular Biology | 11 | 19% |
Medicine and Dentistry | 7 | 12% |
Computer Science | 2 | 3% |
Immunology and Microbiology | 1 | 2% |
Other | 3 | 5% |
Unknown | 16 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2014.
All research outputs
#7,437,326
of 22,757,090 outputs
Outputs from Current Pediatrics Reports
#34
of 84 outputs
Outputs of similar age
#73,355
of 220,834 outputs
Outputs of similar age from Current Pediatrics Reports
#3
of 3 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 84 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,834 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.