| Title |
Autism and gastrointestinal symptoms
|
|---|---|
| Published in |
Current Gastroenterology Reports, June 2002
|
| DOI | 10.1007/s11894-002-0071-6 |
| Pubmed ID | |
| Authors |
Karoly Horvath, Jay A. Perman |
| Abstract |
Autism is a collection of behavioral symptoms characterized by dysfunction in social interaction and communication in affected children. It is typically associated with restrictive, repetitive, and stereotypic behavior and manifests within the first 3 years of life. The cause of this disorder is not known. Over the past decade, a significant upswing in research has occurred to examine the biologic basis of autism. Recent clinical studies have revealed a high prevalence of gastrointestinal symptoms, inflammation, and dysfunction in children with autism. Mild to moderate degrees of inflammation were found in both the upper and lower intestinal tract. In addition, decreased sulfation capacity of the liver, pathologic intestinal permeability, increased secretory response to intravenous secretin injection, and decreased digestive enzyme activities were reported in many children with autism. Treatment of digestive problems appears to have positive effects on autistic behavior. These new observations represent only a piece of the unsolved autism "puzzle" and should stimulate more research into the brain-gut connection. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Netherlands | 1 | <1% |
| Greece | 1 | <1% |
| Ireland | 1 | <1% |
| Unknown | 171 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 29 | 17% |
| Student > Master | 27 | 15% |
| Student > Ph. D. Student | 26 | 15% |
| Researcher | 17 | 10% |
| Student > Doctoral Student | 16 | 9% |
| Other | 28 | 16% |
| Unknown | 32 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 17% |
| Agricultural and Biological Sciences | 17 | 10% |
| Neuroscience | 17 | 10% |
| Psychology | 14 | 8% |
| Nursing and Health Professions | 11 | 6% |
| Other | 43 | 25% |
| Unknown | 43 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2023.
All research outputs
#1,832,113
of 26,017,215 outputs
Outputs from Current Gastroenterology Reports
#52
of 609 outputs
Outputs of similar age
#2,060
of 129,137 outputs
Outputs of similar age from Current Gastroenterology Reports
#1
of 3 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 609 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 129,137 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them