| Title |
Ultra-rapid management of oral anticoagulant therapy-related surgical intracranial hemorrhage
|
|---|---|
| Published in |
Intensive Care Medicine, January 2007
|
| DOI | 10.1007/s00134-007-0528-z |
| Pubmed ID | |
| Authors |
Bernard Vigué, Catherine Ract, Benjamin Tremey, Nicolas Engrand, Pierre Etienne Leblanc, Anne Decaux, Laurent Martin, Dan Benhamou |
| Abstract |
Intracranial hemorrhage in patients receiving oral anticoagulant (OAC) therapy is associated with poor neurological outcome. Prothrombin complex concentrate (PCC) is the gold-standard therapy to normalize hemostasis but remains underused. Ultra-rapid reversal of anticoagulation could reduce the time to biological and surgical hemostasis, and might improve outcome. We report the use of bolus infusions of PCC to immediately reverse anticoagulation and allow for urgent neurosurgical care. |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 4 | 4% |
| Brazil | 1 | 1% |
| France | 1 | 1% |
| Belgium | 1 | 1% |
| United Kingdom | 1 | 1% |
| Unknown | 85 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 16 | 17% |
| Researcher | 13 | 14% |
| Student > Master | 12 | 13% |
| Student > Ph. D. Student | 11 | 12% |
| Student > Postgraduate | 11 | 12% |
| Other | 25 | 27% |
| Unknown | 5 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 61 | 66% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Psychology | 4 | 4% |
| Computer Science | 4 | 4% |
| Neuroscience | 3 | 3% |
| Other | 8 | 9% |
| Unknown | 8 | 9% |