Title |
Low infectivity of a novel avian-origin H7N9 influenza virus in pigs
|
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Published in |
Archives of Virology, June 2014
|
DOI | 10.1007/s00705-014-2143-y |
Pubmed ID | |
Authors |
Jung Yum, Eun Hye Park, Keun Bon Ku, Ji An Kim, Seung Kyoo Oh, Hyun Soo Kim, Sang Heui Seo |
Abstract |
We studied the pathogenesis and transmissibility of a novel avian-origin H7N9 influenza virus in pigs. When pigs were infected with H7N9 influenza virus, they did not show any clear clinical signs (such as sneezing, fever and loss of body weight), and they shed viruses through their noses for 2 days after infection. No transmission occurred between infected and naïve pigs. Pigs suffered from mild pneumonia, which was accompanied by the induction of inflammatory cytokines and chemokines such as IL-8 and CCL1. Taken together, our results suggest that pigs may not play an active role in transmitting H7N9 influenza virus to mammals. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Denmark | 1 | 7% |
Unknown | 14 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 33% |
Student > Master | 3 | 20% |
Student > Ph. D. Student | 3 | 20% |
Student > Bachelor | 1 | 7% |
Professor | 1 | 7% |
Other | 1 | 7% |
Unknown | 1 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 40% |
Medicine and Dentistry | 3 | 20% |
Biochemistry, Genetics and Molecular Biology | 2 | 13% |
Veterinary Science and Veterinary Medicine | 1 | 7% |
Immunology and Microbiology | 1 | 7% |
Other | 1 | 7% |
Unknown | 1 | 7% |