Title |
Systematic Reviews to Ascertain the Safety of Diabetes Medications
|
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Published in |
Current Diabetes Reports, February 2014
|
DOI | 10.1007/s11892-014-0478-0 |
Pubmed ID | |
Authors |
Michael R. Gionfriddo, Oscar L. Morey-Vargas, Juan P. Brito, Aaron L. Leppin, M. Hassan Murad, Victor M. Montori |
Abstract |
Clinicians and patients with type 2 diabetes enjoy an expanding list of medications to improve glycemic control. With this expansion has come a flurry of concerns about the safety of these antihyperglycemic agents, concerns that affect judgments about the risk/benefit balance of therapy. Some of these safety signals have been identified through the synthesis of existing research evidence. Thus, it has become important for clinicians and clinical policymakers to understand the strengths and limitations of systematic reviews and meta-analyses in determining the safety of diabetes medications. In this paper, we highlight key safety concerns with diabetes medications and discuss the role evidence synthesis plays in each, with special attention to its strengths and limitations. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
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Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 3 | 21% |
Student > Doctoral Student | 2 | 14% |
Student > Bachelor | 2 | 14% |
Other | 1 | 7% |
Researcher | 1 | 7% |
Other | 2 | 14% |
Unknown | 3 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 43% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
Computer Science | 1 | 7% |
Agricultural and Biological Sciences | 1 | 7% |
Other | 0 | 0% |
Unknown | 4 | 29% |