| Title |
Effect of screening for type 2 diabetes on risk of cardiovascular disease and mortality: a controlled trial among 139,075 individuals diagnosed with diabetes in Denmark between 2001 and 2009
|
|---|---|
| Published in |
Diabetologia, August 2017
|
| DOI | 10.1007/s00125-017-4299-y |
| Pubmed ID | |
| Authors |
Rebecca K. Simmons, Simon J. Griffin, Torsten Lauritzen, Annelli Sandbæk |
| Abstract |
There is continuing debate about the net benefits of population screening for type 2 diabetes. We compared the risk of cardiovascular disease (CVD) and mortality among incident cases of type 2 diabetes in a screened group with those in an unscreened group. In this register-based non-randomised controlled trial, eligible individuals were all men and women aged 40-69 years without known diabetes, registered with a general practice in Denmark (n = 1,912,392). Between 2001 and 2006, 153,107 individuals registered with 181 practices participating in the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION)-Denmark study were sent a diabetes-risk-score questionnaire. Individuals at moderate-to-high risk were invited to visit their family doctor for assessment of diabetes status and cardiovascular risk (screening group). The 1,759,285 individuals registered with all other practices in Denmark constituted the retrospectively constructed no-screening (control) group. In this post hoc analysis, we identified individuals from the screening and no-screening groups who were diagnosed with diabetes between 2001 and 2009 (n = 139,075), and compared risk of CVD and mortality in these groups between 2001 and 2012. In the screening group, 27,177/153,107 (18%) individuals attended for screening, of whom 1533 were diagnosed with diabetes. Between 2001 and 2009, 13,992 people were newly diagnosed with diabetes in the screening group (including those diagnosed by screening) and 125,083 in the no-screening group. Between 2001 and 2012, the risks of CVD and mortality were lower among individuals with diabetes in the screening group compared with individuals with diabetes in the no-screening (control) group (CVD HR 0.84, 95% CI 0.80, 0.89; mortality HR 0.79, 95% CI 0.74, 0.84). A single round of diabetes screening and cardiovascular risk assessment in middle-aged Danish adults in general practice was associated with a significant reduction in risk of all-cause mortality and CVD events in those diagnosed with diabetes. |
X Demographics
The data shown below were collected from the profiles of 50 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 14 | 28% |
| Spain | 9 | 18% |
| India | 2 | 4% |
| Mexico | 1 | 2% |
| Denmark | 1 | 2% |
| Colombia | 1 | 2% |
| United States | 1 | 2% |
| Netherlands | 1 | 2% |
| Croatia | 1 | 2% |
| Other | 4 | 8% |
| Unknown | 15 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 30 | 60% |
| Practitioners (doctors, other healthcare professionals) | 11 | 22% |
| Scientists | 8 | 16% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 124 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 21 | 17% |
| Student > Master | 19 | 15% |
| Researcher | 15 | 12% |
| Student > Ph. D. Student | 12 | 10% |
| Student > Postgraduate | 8 | 6% |
| Other | 17 | 14% |
| Unknown | 32 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 47 | 38% |
| Nursing and Health Professions | 10 | 8% |
| Agricultural and Biological Sciences | 4 | 3% |
| Biochemistry, Genetics and Molecular Biology | 4 | 3% |
| Social Sciences | 4 | 3% |
| Other | 13 | 10% |
| Unknown | 42 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 91. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2020.
All research outputs
#474,420
of 25,732,188 outputs
Outputs from Diabetologia
#245
of 5,376 outputs
Outputs of similar age
#9,890
of 326,017 outputs
Outputs of similar age from Diabetologia
#11
of 107 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,376 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.7. This one has done particularly well, scoring higher than 95% of its peers.
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We're also able to compare this research output to 107 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.