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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?
|
|---|---|
| Published in |
International Journal of Cancer, June 2014
|
| DOI | 10.1002/ijc.29003 |
| Pubmed ID | |
| Authors |
Ronan F. Downey, Francis J. Sullivan, Feng Wang-Johanning, Stefan Ambs, Francis J. Giles, Sharon A. Glynn |
| Abstract |
Harbored as relics of ancient germline infections, human endogenous retroviruses (HERVs) now constitute up to 8% of our genome. A proportion of this sequence has been co-opted for molecular and cellular processes, beneficial to human physiology, such as the fusogenic activity of the envelope protein, a vital component of placentogenesis. However, the discovery of high levels of HERV-K mRNA and protein and even virions in a wide array of cancers, has revealed that HERV-K may be playing a more sinister role - a role as an etiological agent in cancer itself. Whether the presence of this retroviral material is simply an epiphenomenon, or an actual causative factor, is a hotly debated topic. This review will summarize the current state of knowledge regarding HERV-K and cancer and attempt to outline the potential mechanisms by which HERV-K could be involved in the onset and promotion of carcinogenesis. © 2014 Wiley Periodicals, Inc. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Brazil | 1 | <1% |
| Canada | 1 | <1% |
| Belgium | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 161 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 19% |
| Student > Master | 30 | 18% |
| Researcher | 26 | 16% |
| Student > Bachelor | 23 | 14% |
| Student > Postgraduate | 11 | 7% |
| Other | 25 | 15% |
| Unknown | 20 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 44 | 27% |
| Biochemistry, Genetics and Molecular Biology | 35 | 21% |
| Medicine and Dentistry | 31 | 19% |
| Immunology and Microbiology | 12 | 7% |
| Engineering | 5 | 3% |
| Other | 13 | 8% |
| Unknown | 26 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2024.
All research outputs
#6,942,073
of 25,119,447 outputs
Outputs from International Journal of Cancer
#4,336
of 12,210 outputs
Outputs of similar age
#60,917
of 234,318 outputs
Outputs of similar age from International Journal of Cancer
#41
of 116 outputs
Altmetric has tracked 25,119,447 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 12,210 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 234,318 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.