Title |
Intrawound vancomycin to prevent infections after spine surgery: a systematic review and meta-analysis
|
---|---|
Published in |
European Spine Journal, May 2014
|
DOI | 10.1007/s00586-014-3357-0 |
Pubmed ID | |
Authors |
Nathan Evaniew, Moin Khan, Brian Drew, Devin Peterson, Mohit Bhandari, Michelle Ghert |
Abstract |
Post-operative spine surgical site infections are associated with substantial morbidity, mortality, and economic burden. Intrawound vancomycin may prevent infections after spine surgery, but recent studies have reported conflicting results. The objectives of this systematic review and meta-analysis were to determine: (1) In patients undergoing spine surgery, does the application of intrawound vancomycin lead to reduced rates of post-operative surgical site infections? (2) Are there differences in the estimates of effect between observational studies and randomized trials? (3) What adverse events are reported in the literature? |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
Lebanon | 1 | 1% |
United States | 1 | 1% |
Unknown | 90 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 15% |
Other | 13 | 14% |
Student > Postgraduate | 7 | 8% |
Student > Bachelor | 7 | 8% |
Student > Ph. D. Student | 6 | 6% |
Other | 20 | 22% |
Unknown | 26 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 46 | 49% |
Neuroscience | 3 | 3% |
Nursing and Health Professions | 2 | 2% |
Agricultural and Biological Sciences | 1 | 1% |
Immunology and Microbiology | 1 | 1% |
Other | 4 | 4% |
Unknown | 36 | 39% |