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Intrawound vancomycin to prevent infections after spine surgery: a systematic review and meta-analysis

Overview of attention for article published in European Spine Journal, May 2014
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Title
Intrawound vancomycin to prevent infections after spine surgery: a systematic review and meta-analysis
Published in
European Spine Journal, May 2014
DOI 10.1007/s00586-014-3357-0
Pubmed ID
Authors

Nathan Evaniew, Moin Khan, Brian Drew, Devin Peterson, Mohit Bhandari, Michelle Ghert

Abstract

Post-operative spine surgical site infections are associated with substantial morbidity, mortality, and economic burden. Intrawound vancomycin may prevent infections after spine surgery, but recent studies have reported conflicting results. The objectives of this systematic review and meta-analysis were to determine: (1) In patients undergoing spine surgery, does the application of intrawound vancomycin lead to reduced rates of post-operative surgical site infections? (2) Are there differences in the estimates of effect between observational studies and randomized trials? (3) What adverse events are reported in the literature?

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Lebanon 1 1%
United States 1 1%
Unknown 90 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 15%
Other 13 14%
Student > Postgraduate 7 8%
Student > Bachelor 7 8%
Student > Ph. D. Student 6 6%
Other 20 22%
Unknown 26 28%
Readers by discipline Count As %
Medicine and Dentistry 46 49%
Neuroscience 3 3%
Nursing and Health Professions 2 2%
Agricultural and Biological Sciences 1 1%
Immunology and Microbiology 1 1%
Other 4 4%
Unknown 36 39%