| Title |
Antifungal Metabolites Produced by Chaetomium globosum No.04, an Endophytic Fungus Isolated from Ginkgo biloba
|
|---|---|
| Published in |
Indian Journal of Microbiology, February 2013
|
| DOI | 10.1007/s12088-013-0362-7 |
| Pubmed ID | |
| Authors |
Guizhen Zhang, Yanhua Zhang, Jianchun Qin, Xiaoyan Qu, Jinliang Liu, Xiang Li, Hongyu Pan |
| Abstract |
The fungal endophyte Chaetomium globosum No.04 was isolated from the medicinal plant Ginkgo biloba. The crude extract of the fungus fermentation were active in the agar-diffusion tests against the phytopathogenic fungi Rhizopus stolonifer and Coniothyrium diplodiella. Further bioassay-guided chemical investigation led to the isolation and purification of six alkaloids and three non-targeted compounds from 50 L fermentation of this endophytic fungus and their structures were elucidated as chaetoglobosin A, C, D, E, G, R (1-6), ergosterol, allantoin and uracil, by means of spectroscopic analysis. Compounds 1-6 showed significant growth inhibitory activity against R. stolonifer and C. diplodiella at a concentration of 20 μg/disc. We present here, for the first time, the potent antifungal activity of chaetoglobosins from endophytic fungi against two important phytopathogenic fungi R. stolonifer and C. diplodiella. |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Austria | 1 | 2% |
| Unknown | 47 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 17% |
| Researcher | 6 | 13% |
| Student > Bachelor | 5 | 10% |
| Student > Master | 4 | 8% |
| Professor | 3 | 6% |
| Other | 10 | 21% |
| Unknown | 12 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 23 | 48% |
| Biochemistry, Genetics and Molecular Biology | 5 | 10% |
| Chemistry | 4 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Immunology and Microbiology | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 13 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2014.
All research outputs
#20,231,392
of 22,757,090 outputs
Outputs from Indian Journal of Microbiology
#285
of 382 outputs
Outputs of similar age
#252,020
of 285,666 outputs
Outputs of similar age from Indian Journal of Microbiology
#8
of 8 outputs
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So far Altmetric has tracked 382 research outputs from this source. They receive a mean Attention Score of 2.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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