| Title |
Pan-metazoan phylogeny of the DMRT gene family: a framework for functional studies
|
|---|---|
| Published in |
Development Genes and Evolution, June 2014
|
| DOI | 10.1007/s00427-014-0473-0 |
| Pubmed ID | |
| Authors |
Judith R. Wexler, David C. Plachetzki, Artyom Kopp |
| Abstract |
The family of Doublesex-Mab-3 Related Transcription factors (DMRTs) includes key regulators of sexual differentiation and neurogenesis. To help understand the functional diversification of this gene family, we examined DMRT gene complements from the whole genome sequences and predicted gene models of 32 animal species representing 12 different phyla and from several non-metazoan outgroups. DMRTs are present in all animals except the sponge Amphimedon queenslandica, but are not found in any of the outgroups, indicating that this gene family is specific to animals and has an ancient pre-eumetazoan origin. Our analyses suggest that DMRT genes diversified independently in bilaterian and non-bilaterian animals. Most clades in the DMRT gene tree, including those containing the well-characterized DMRT1 and doublesex genes, have phylogenetically limited distributions. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Saudi Arabia | 1 | 2% |
| Unknown | 53 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 25% |
| Student > Master | 10 | 18% |
| Student > Bachelor | 7 | 13% |
| Researcher | 7 | 13% |
| Student > Postgraduate | 3 | 5% |
| Other | 6 | 11% |
| Unknown | 8 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 21 | 38% |
| Agricultural and Biological Sciences | 18 | 33% |
| Environmental Science | 1 | 2% |
| Nursing and Health Professions | 1 | 2% |
| Business, Management and Accounting | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 11 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2014.
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#14,065,859
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Outputs of similar age from Development Genes and Evolution
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