| Title |
Cancer Immunotherapy and Nanomedicine
|
|---|---|
| Published in |
Pharmaceutical Research, September 2010
|
| DOI | 10.1007/s11095-010-0258-8 |
| Pubmed ID | |
| Authors |
Wei-Yun Sheng, Leaf Huang |
| Abstract |
The immune system has the ability to recognize and kill pre-cancer and cancer cells. However, with the immune system's surveillance, the survival tumor cells learn how to escape the immune system after immunoselection. Cancer immunotherapy develops strategies to overcome these problems. Nanomedicine applications in cancer immunotherapy include the nanodiagnostics and nanobiopharmaceuticals. In cancer nanodiagnostics, it looks for specific "molecular signatures" in cancer cells or their microenvironment by using genomics and proteomics. Nanobiopharmaceuticals is the field that studies nanotechnology-based therapeutic agents and drug carriers. DNA, RNA, peptides, proteins and small molecules can all be used as cancer therapies when formulated in nanocarriers. Currently, cancer vaccines are applied in treatments with existing cancer or to prevent the development of cancer in certain high risk individuals. Most of the non-specific immune activation agents include adjuvants which enhance immunogenicity and accelerate and prolong the response of cancer vaccines. The carriers of vaccines, such as viruses and nanoparticles, have also been in clinical studies for many years. This review will discuss the relationships between the tumor and the immune system, and also will include topics covering the strategies used in eliminating tumors by using nanomedicine. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| Brazil | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Spain | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Unknown | 120 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 23% |
| Student > Master | 20 | 16% |
| Researcher | 19 | 15% |
| Student > Bachelor | 10 | 8% |
| Student > Doctoral Student | 6 | 5% |
| Other | 17 | 13% |
| Unknown | 27 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 21% |
| Medicine and Dentistry | 18 | 14% |
| Biochemistry, Genetics and Molecular Biology | 11 | 9% |
| Chemistry | 11 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Other | 23 | 18% |
| Unknown | 32 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2011.
All research outputs
#15,234,609
of 22,651,245 outputs
Outputs from Pharmaceutical Research
#2,232
of 2,846 outputs
Outputs of similar age
#76,396
of 94,722 outputs
Outputs of similar age from Pharmaceutical Research
#32
of 32 outputs
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