| Title |
Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes
|
|---|---|
| Published in |
Molecular Cancer, June 2014
|
| DOI | 10.1186/1476-4598-13-151 |
| Pubmed ID | |
| Authors |
Nathalie Martin, Clara Salazar-Cardozo, Chantal Vercamer, Louise Ott, Guillemette Marot, Predrag Slijepcevic, Corinne Abbadie, Olivier Pluquet |
| Abstract |
Epidemiological data show that the incidence of carcinomas in humans is highly dependent on age. However, the initial steps of the age-related molecular oncogenic processes by which the switch towards the neoplastic state occurs remain poorly understood, mostly due to the absence of powerful models. In a previous study, we showed that normal human epidermal keratinocytes (NHEKs) spontaneously and systematically escape from senescence to give rise to pre-neoplastic emerging cells. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 33 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 24% |
| Student > Ph. D. Student | 8 | 24% |
| Student > Bachelor | 4 | 12% |
| Student > Postgraduate | 2 | 6% |
| Other | 2 | 6% |
| Other | 4 | 12% |
| Unknown | 5 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 10 | 30% |
| Agricultural and Biological Sciences | 8 | 24% |
| Medicine and Dentistry | 5 | 15% |
| Computer Science | 1 | 3% |
| Social Sciences | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 5 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2014.
All research outputs
#15,301,754
of 22,757,090 outputs
Outputs from Molecular Cancer
#1,042
of 1,718 outputs
Outputs of similar age
#133,310
of 228,190 outputs
Outputs of similar age from Molecular Cancer
#25
of 47 outputs
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