| Title |
Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina
|
|---|---|
| Published in |
BMC Ophthalmology, August 2011
|
| DOI | 10.1186/1471-2415-11-22 |
| Pubmed ID | |
| Authors |
Bhanu Dasari, Jaya RP Prasanthi, Gurdeep Marwarha, Brij B Singh, Othman Ghribi |
| Abstract |
Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological hallmarks including β-amyloid (Aβ) accumulation, oxidative stress, and apoptotic cell death. The causes of AD and AMD are likely multi-factorial with several factors such as diet, environment, and genetic susceptibility participating in the pathogenesis of these diseases. Epidemiological studies correlated high plasma cholesterol levels with high incidence of AD, and feeding rabbits with a diet rich in cholesterol has been shown to induce AD-like pathology in rabbit brain. High intake of cholesterol and saturated fat were also long been suspected to increase the risk for AMD. However, the extent to which cholesterol-enriched diet may also cause AMD-like features in rabbit retinas is not well known. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 76 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 19% |
| Student > Bachelor | 14 | 18% |
| Researcher | 10 | 13% |
| Student > Postgraduate | 5 | 6% |
| Professor > Associate Professor | 5 | 6% |
| Other | 14 | 18% |
| Unknown | 14 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 31% |
| Agricultural and Biological Sciences | 14 | 18% |
| Biochemistry, Genetics and Molecular Biology | 5 | 6% |
| Neuroscience | 3 | 4% |
| Nursing and Health Professions | 2 | 3% |
| Other | 13 | 17% |
| Unknown | 16 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2023.
All research outputs
#2,376,297
of 23,505,669 outputs
Outputs from BMC Ophthalmology
#97
of 2,502 outputs
Outputs of similar age
#11,589
of 124,723 outputs
Outputs of similar age from BMC Ophthalmology
#1
of 3 outputs
Altmetric has tracked 23,505,669 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,502 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done particularly well, scoring higher than 96% of its peers.
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We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them